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Gnotobiotic piglets were infected with a strain of rotavirus that had been isolated from a calf and passaged four times in piglets. The resulting disease was studied by light and electron microscopy at 21, 44 and 68 h after inoculation. In the small intestine infection caused desquamation of the epithelial cells of the villi resulting in severe stunting. There was severe damage to microvilli and accumulation of lipid within the cytoplasm. Virus particles were seen in epithelial cells covering the stunted villi. Infection also caused desquamation of the superficial epithelial cells of the stomach mucosa and of the epithelial cells of the bronchi, bronchioles, and alveoli of the lungs.
G A Hall, and
J C Bridger, and
R L Chandler, and
G N Woode
January 1976,
Annales de recherches veterinaires. Annals of veterinary research,
G A Hall, and
J C Bridger, and
R L Chandler, and
G N Woode
January 1976,
Intervirology,
G A Hall, and
J C Bridger, and
R L Chandler, and
G N Woode
January 1975,
The British veterinary journal,
G A Hall, and
J C Bridger, and
R L Chandler, and
G N Woode
January 1978,
Microbiology and immunology,
G A Hall, and
J C Bridger, and
R L Chandler, and
G N Woode
May 1977,
American journal of veterinary research,
G A Hall, and
J C Bridger, and
R L Chandler, and
G N Woode
January 1973,
Veterinary pathology,
G A Hall, and
J C Bridger, and
R L Chandler, and
G N Woode
January 1982,
National Institute of Animal Health quarterly,
G A Hall, and
J C Bridger, and
R L Chandler, and
G N Woode
January 1976,
The Journal of infectious diseases,
G A Hall, and
J C Bridger, and
R L Chandler, and
G N Woode
July 1977,
Journal of comparative pathology,
G A Hall, and
J C Bridger, and
R L Chandler, and
G N Woode
January 1977,
Research in veterinary science,
