[Visualization of epileptic foci using 99mTc-HM-PAO in SPECT]. 1991

I Nikolić, and D Mitrović
Institut za patolosku fiziologiju i laboratorijsku dijagnostiku, Medicinski fakultet Novi Sad.

A case of a 16 year old female patient with complex partial seizures has been presented. At the beginning of the illness the seizure focus had been located on the left temporal region according to the EEG finding and the clinical manifestation. Later on the epileptic focus changed sides to the right temporal region. The CT finding of this patient had been normal and the SPECT-HM-PAO method revealed a significant reduction of rCBF in the parietotemporal region of the left hemisphere, as well as the existence of a region of hyperperfusion in the right temporal lobe.

UI MeSH Term Description Entries
D010091 Oximes Compounds that contain the radical R2C Aldoximes,Hydroxyimino Compounds,Ketoxime,Ketoximes,Oxime,Compounds, Hydroxyimino
D001921 Brain The part of CENTRAL NERVOUS SYSTEM that is contained within the skull (CRANIUM). Arising from the NEURAL TUBE, the embryonic brain is comprised of three major parts including PROSENCEPHALON (the forebrain); MESENCEPHALON (the midbrain); and RHOMBENCEPHALON (the hindbrain). The developed brain consists of CEREBRUM; CEREBELLUM; and other structures in the BRAIN STEM. Encephalon
D002560 Cerebrovascular Circulation The circulation of blood through the BLOOD VESSELS of the BRAIN. Brain Blood Flow,Regional Cerebral Blood Flow,Cerebral Blood Flow,Cerebral Circulation,Cerebral Perfusion Pressure,Circulation, Cerebrovascular,Blood Flow, Brain,Blood Flow, Cerebral,Brain Blood Flows,Cerebral Blood Flows,Cerebral Circulations,Cerebral Perfusion Pressures,Circulation, Cerebral,Flow, Brain Blood,Flow, Cerebral Blood,Perfusion Pressure, Cerebral,Pressure, Cerebral Perfusion
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293 Adolescent A person 13 to 18 years of age. Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D015609 Organotechnetium Compounds Organic compounds that contain technetium as an integral part of the molecule. These compounds are often used as radionuclide imaging agents. Compounds, Organotechnetium
D015899 Tomography, Emission-Computed, Single-Photon A method of computed tomography that uses radionuclides which emit a single photon of a given energy. The camera is rotated 180 or 360 degrees around the patient to capture images at multiple positions along the arc. The computer is then used to reconstruct the transaxial, sagittal, and coronal images from the 3-dimensional distribution of radionuclides in the organ. The advantages of SPECT are that it can be used to observe biochemical and physiological processes as well as size and volume of the organ. The disadvantage is that, unlike positron-emission tomography where the positron-electron annihilation results in the emission of 2 photons at 180 degrees from each other, SPECT requires physical collimation to line up the photons, which results in the loss of many available photons and hence degrades the image. CAT Scan, Single-Photon Emission,CT Scan, Single-Photon Emission,Radionuclide Tomography, Single-Photon Emission-Computed,SPECT,Single-Photon Emission-Computed Tomography,Tomography, Single-Photon, Emission-Computed,Single-Photon Emission CT Scan,Single-Photon Emission Computer-Assisted Tomography,Single-Photon Emission Computerized Tomography,CAT Scan, Single Photon Emission,CT Scan, Single Photon Emission,Emission-Computed Tomography, Single-Photon,Radionuclide Tomography, Single Photon Emission Computed,Single Photon Emission CT Scan,Single Photon Emission Computed Tomography,Single Photon Emission Computer Assisted Tomography,Single Photon Emission Computerized Tomography,Tomography, Single-Photon Emission-Computed
D017029 Epilepsy, Complex Partial A disorder characterized by recurrent partial seizures marked by impairment of cognition. During the seizure the individual may experience a wide variety of psychic phenomenon including formed hallucinations, illusions, deja vu, intense emotional feelings, confusion, and spatial disorientation. Focal motor activity, sensory alterations and AUTOMATISM may also occur. Complex partial seizures often originate from foci in one or both temporal lobes. The etiology may be idiopathic (cryptogenic partial complex epilepsy) or occur as a secondary manifestation of a focal cortical lesion (symptomatic partial complex epilepsy). (From Adams et al., Principles of Neurology, 6th ed, pp317-8) Complex Partial Epilepsy,Complex Partial Seizure Disorder,Cryptogenic Partial Complex Epilepsy,Disorder, Complex Partial Seizures,Epilepsy, Cryptogenic, Partial Complex,Epilepsy, Psychic Equivalent,Epilepsy, Psychomotor,Epilepsy, Symptomatic, Partial Complex,Partial Complex Epilepsy, Cryptogenic,Partial Complex Epilepsy, Symptomatic,Seizure Disorder, Complex Partial,Symptomatic Partial Complex Epilepsy,Partial Epilepsy, Complex,Psychic Equivalent Epilepsy,Psychomotor Epilepsy
D019690 Technetium Tc 99m Exametazime A gamma-emitting RADIONUCLIDE IMAGING agent used in the evaluation of regional cerebral blood flow and in non-invasive dynamic biodistribution studies and MYOCARDIAL PERFUSION IMAGING. It has also been used to label leukocytes in the investigation of INFLAMMATORY BOWEL DISEASES. Tc-99m HMPAO,Technetium Tc 99m Hexamethylpropyleneamine Oxime,99m-Tc-HMPAO,99mTc-HMPAO,Ceretec,Tc-99m-Exametazime,Tc-99m-Hexamethylpropyleneamine Oxime,Technetium Tc 99m Hexamethylpropylene-amine Oxime,Tc 99m Exametazime,Tc 99m Hexamethylpropyleneamine Oxime,Technetium Tc 99m Hexamethylpropylene amine Oxime

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