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The Sanarelli-Shwartzman phenomenon and sanergy. 1949

S LEWI

UI MeSH Term Description Entries
D012790 Shwartzman Phenomenon Hemorrhagic necrosis that was first demonstrated in rabbits with a two-step reaction, an initial local (intradermal) or general (intravenous) injection of a priming endotoxin (ENDOTOXINS) followed by a second intravenous endotoxin injection (provoking agent) 24 h later. The acute inflammation damages the small blood vessels. The following intravascular coagulation leads to capillary and venous THROMBOSIS and NECROSIS. Shwartzman phenomenon can also occur in other species with a single injection of a provoking agent, and during infections or pregnancy. Its susceptibility depends on the status of IMMUNE SYSTEM, coagulation, FIBRINOLYSIS, and blood flow. Schwartzman Phenomenon,Shwartzman Reaction,Schwartzman Reaction,Phenomenon, Schwartzman,Phenomenon, Shwartzman,Schwartzman Reactions

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