-transparent.png){kind=logo}
The relationship between polyneuropathies and monoclonal gammopathies is well known even though the pathogenetic hypotheses are controversial. The role of autoantibodies against neural antigens has been recently underlined. 45 patients (29 M and 16 F), affected by multiple myeloma (MM) non-Hodgkin lymphoma (NHL) with paraproteinemia and monoclonal gammopathies of undetermined significance (MGUS)4, underwent an EMG study including SCV, MCV and late responses of several nerves, and a search for serum antibodies against neural antigens by immunoblotting assay. 19 out of 45 pts. tested positive to EMG and 15 out of 45 (10 MM and 5 NHL) showed a serological positivity. Among them 11 were positive to EMG too. The results confirm the hypothesis of a possible pathogenetic role of high-titer autoantibodies against neural antigens in cases of polyneuropathy.
L Guardigni, and
F Rasi, and
R Nemni, and
I Lorenzetti, and
F Valzania, and
E Pretolani
October 2009,
Current opinion in neurology,
L Guardigni, and
F Rasi, and
R Nemni, and
I Lorenzetti, and
F Valzania, and
E Pretolani
June 1992,
Annals of neurology,
L Guardigni, and
F Rasi, and
R Nemni, and
I Lorenzetti, and
F Valzania, and
E Pretolani
June 1992,
Annals of neurology,
L Guardigni, and
F Rasi, and
R Nemni, and
I Lorenzetti, and
F Valzania, and
E Pretolani
October 1996,
Current opinion in neurology,
L Guardigni, and
F Rasi, and
R Nemni, and
I Lorenzetti, and
F Valzania, and
E Pretolani
January 2013,
Handbook of clinical neurology,
L Guardigni, and
F Rasi, and
R Nemni, and
I Lorenzetti, and
F Valzania, and
E Pretolani
October 2007,
Current opinion in neurology,
L Guardigni, and
F Rasi, and
R Nemni, and
I Lorenzetti, and
F Valzania, and
E Pretolani
October 2001,
Current opinion in neurology,
L Guardigni, and
F Rasi, and
R Nemni, and
I Lorenzetti, and
F Valzania, and
E Pretolani
March 1990,
Schweizerische medizinische Wochenschrift,
L Guardigni, and
F Rasi, and
R Nemni, and
I Lorenzetti, and
F Valzania, and
E Pretolani
May 2000,
Archives of neurology,
L Guardigni, and
F Rasi, and
R Nemni, and
I Lorenzetti, and
F Valzania, and
E Pretolani
May 2006,
Leukemia & lymphoma,
