Permanent pacemaker implantation after isolated aortic valve replacement: incidence, indications, and predictors. 2008

Sam Dawkins, and Alex R Hobson, and Paul R Kalra, and Augustine T M Tang, and James L Monro, and Keith D Dawkins
Wessex Cardiac Unit, Southampton University Hospital, Southampton, United Kingdom.

BACKGROUND Conducting system defects are common in patients with aortic valve disease. Aortic valve replacement may result in further conduction abnormalities and necessitate permanent pacemaker implantation (PPM). We sought to identify the contemporary incidence and predictors for early postoperative PPM in patients undergoing isolated aortic valve replacement. METHODS Data were analyzed from 354 consecutive patients undergoing isolated aortic valve replacement at a referral cardiac unit during a 30-month period; data were unavailable on 4 patients and a further 8 had undergone preoperative PPM. Results for the remaining 342 patients (97%; mean age, 67 +/- 14 years), of whom 212 were males, are presented. The major indications for aortic valve replacement were valvular stenosis (n = 224), regurgitation (n = 70), or infective endocarditis (n = 25). Preoperative conducting system disease was present in 26% of patients. RESULTS In-hospital mortality was 1.8% (6 of 342 patients). Postoperatively 29 patients (8.5%) required early PPM, of which 26 were during the index admission. Patients with preoperative conducting system disease (16% versus 6%; p = 0.004) and valvular regurgitation (16% versus 7%; p = 0.01) were more likely to require PPM as opposed to those without. Preoperative conducting system disease was the only independent predictor of PPM (p < 0.01); the relative risk of PPM requirement in this group was 2.88 (95% confidence interval, 1.31 to 6.33). CONCLUSIONS Permanent pacemaker implantation requirement after aortic valve replacement is a common occurrence, and should be discussed as part of the preoperative consent process. Preexisting conducting disease and preoperative aortic regurgitation were predictors of PPM requirement.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010138 Pacemaker, Artificial A device designed to stimulate, by electric impulses, contraction of the heart muscles. It may be temporary (external) or permanent (internal or internal-external). Cardiac Pacemaker, Artificial,Artificial Cardiac Pacemaker,Artificial Cardiac Pacemakers,Artificial Pacemaker,Artificial Pacemakers,Cardiac Pacemakers, Artificial,Pacemaker, Artificial Cardiac,Pacemakers, Artificial,Pacemakers, Artificial Cardiac
D011183 Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D011237 Predictive Value of Tests In screening and diagnostic tests, the probability that a person with a positive test is a true positive (i.e., has the disease), is referred to as the predictive value of a positive test; whereas, the predictive value of a negative test is the probability that the person with a negative test does not have the disease. Predictive value is related to the sensitivity and specificity of the test. Negative Predictive Value,Positive Predictive Value,Predictive Value Of Test,Predictive Values Of Tests,Negative Predictive Values,Positive Predictive Values,Predictive Value, Negative,Predictive Value, Positive
D011336 Probability The study of chance processes or the relative frequency characterizing a chance process. Probabilities
D004562 Electrocardiography Recording of the moment-to-moment electromotive forces of the HEART as projected onto various sites on the body's surface, delineated as a scalar function of time. The recording is monitored by a tracing on slow moving chart paper or by observing it on a cardioscope, which is a CATHODE RAY TUBE DISPLAY. 12-Lead ECG,12-Lead EKG,12-Lead Electrocardiography,Cardiography,ECG,EKG,Electrocardiogram,Electrocardiograph,12 Lead ECG,12 Lead EKG,12 Lead Electrocardiography,12-Lead ECGs,12-Lead EKGs,12-Lead Electrocardiographies,Cardiographies,ECG, 12-Lead,EKG, 12-Lead,Electrocardiograms,Electrocardiographies, 12-Lead,Electrocardiographs,Electrocardiography, 12-Lead
D005260 Female Females
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006329 Heart Conduction System An impulse-conducting system composed of modified cardiac muscle, having the power of spontaneous rhythmicity and conduction more highly developed than the rest of the heart. Conduction System, Heart,Conduction Systems, Heart,Heart Conduction Systems,System, Heart Conduction,Systems, Heart Conduction

Related Publications

Sam Dawkins, and Alex R Hobson, and Paul R Kalra, and Augustine T M Tang, and James L Monro, and Keith D Dawkins
October 2008, The Annals of thoracic surgery,
Sam Dawkins, and Alex R Hobson, and Paul R Kalra, and Augustine T M Tang, and James L Monro, and Keith D Dawkins
October 2015, Journal of cardiothoracic and vascular anesthesia,
Sam Dawkins, and Alex R Hobson, and Paul R Kalra, and Augustine T M Tang, and James L Monro, and Keith D Dawkins
January 2010, Journal of cardiovascular medicine (Hagerstown, Md.),
Sam Dawkins, and Alex R Hobson, and Paul R Kalra, and Augustine T M Tang, and James L Monro, and Keith D Dawkins
January 2018, Pacing and clinical electrophysiology : PACE,
Sam Dawkins, and Alex R Hobson, and Paul R Kalra, and Augustine T M Tang, and James L Monro, and Keith D Dawkins
November 2021, Journal of cardiac surgery,
Sam Dawkins, and Alex R Hobson, and Paul R Kalra, and Augustine T M Tang, and James L Monro, and Keith D Dawkins
September 2020, Interactive cardiovascular and thoracic surgery,
Sam Dawkins, and Alex R Hobson, and Paul R Kalra, and Augustine T M Tang, and James L Monro, and Keith D Dawkins
January 2021, JACC. Cardiovascular interventions,
Sam Dawkins, and Alex R Hobson, and Paul R Kalra, and Augustine T M Tang, and James L Monro, and Keith D Dawkins
September 2018, The Annals of thoracic surgery,
Sam Dawkins, and Alex R Hobson, and Paul R Kalra, and Augustine T M Tang, and James L Monro, and Keith D Dawkins
August 2021, Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing,
Sam Dawkins, and Alex R Hobson, and Paul R Kalra, and Augustine T M Tang, and James L Monro, and Keith D Dawkins
January 2022, Cardiology in review,
Copied contents to your clipboard!