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We did a double blind, crossover, prospective study comparing bicarbonate and acetate containing solutions in haemodialysis. Thirty stable patients with end stage renal disease on maintenance haemodialysis while awaiting a renal transplant were each studied on three dialysis with acetate and three with bicarbonate. Nine patients developed symptoms like headache, nausea, vomiting, giddiness, and malaise and developed hypotension during acetate dialysis and three patients during bicarbonate dialysis. There were symptoms during 16.66% of acetate dialysis sessions and 5.55% of bicarbonate dialysis sessions. (P less than 0.05). There was a statistically significant decrease in PaO2 and PaCO2 on acetate dialysis at 30 minutes after initiation of dialysis. There was no significant difference in weight loss on dialysis, or in blood pressure and correction of acidosis. We conclude that bicarbonate dialysis is better tolerated, but acetate intolerance is not a major problem since we use small surface area dialysers (0.8 M2).
K C Gurudev, and
V Pathak, and
K S Prabhakar, and
S Bhaskar, and
K C Prakash, and
Prabhakaran, and
M K Mani
January 1987,
Minerva urologica e nefrologica = The Italian journal of urology and nephrology,
K C Gurudev, and
V Pathak, and
K S Prabhakar, and
S Bhaskar, and
K C Prakash, and
Prabhakaran, and
M K Mani
January 1993,
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis,
K C Gurudev, and
V Pathak, and
K S Prabhakar, and
S Bhaskar, and
K C Prakash, and
Prabhakaran, and
M K Mani
January 1980,
Nephrology nurse,
K C Gurudev, and
V Pathak, and
K S Prabhakar, and
S Bhaskar, and
K C Prakash, and
Prabhakaran, and
M K Mani
January 1983,
Proceedings of the European Dialysis and Transplant Association. European Dialysis and Transplant Association,
K C Gurudev, and
V Pathak, and
K S Prabhakar, and
S Bhaskar, and
K C Prakash, and
Prabhakaran, and
M K Mani
March 1982,
Kidney international,
K C Gurudev, and
V Pathak, and
K S Prabhakar, and
S Bhaskar, and
K C Prakash, and
Prabhakaran, and
M K Mani
January 1983,
Nephrologie,
K C Gurudev, and
V Pathak, and
K S Prabhakar, and
S Bhaskar, and
K C Prakash, and
Prabhakaran, and
M K Mani
January 1988,
Blood purification,
K C Gurudev, and
V Pathak, and
K S Prabhakar, and
S Bhaskar, and
K C Prakash, and
Prabhakaran, and
M K Mani
January 1981,
Minerva nefrologica,
K C Gurudev, and
V Pathak, and
K S Prabhakar, and
S Bhaskar, and
K C Prakash, and
Prabhakaran, and
M K Mani
December 1992,
The International journal of artificial organs,
K C Gurudev, and
V Pathak, and
K S Prabhakar, and
S Bhaskar, and
K C Prakash, and
Prabhakaran, and
M K Mani
July 1998,
American journal of kidney diseases : the official journal of the National Kidney Foundation,
