Clinical characteristics of patients with dilated cardiomyopathy and bradyarrhythmias. 1991

S Ando, and S Koyanagi, and K Muramatsu, and R Itaya, and A Takeshita, and M Nakamura
Research Institute of Angiocardiology and Cardiovascular Clinic, Faculty of Medicine, Kyushu University, Fukuoka.

The clinical characteristics of patients with dilated cardiomyopathy and bradyarrhythmias were studied. Among 50 patients with dilated cardiomyopathy, 6 had bradyarrhythmias. Among these patients were one with sinus bradycardia, one with atrial fibrillation and slow ventricular responses and sick sinus syndrome (SSS), one with SSS with advanced AV block, and 3 with advanced AV block. The average age at the onset of their cardiac symptoms (60.3 +/- 12.1 years (mean +/- SD)) was significantly (p less than 0.01) higher than that of 43 patients without bradyarrhythmias (40.0 +/- 17.6). The left ventricular diastolic dimension and ejection fraction were similar among patients with and without bradyarrhythmias. In 31 follow-up patients without bradyarrhythmias, 8 (25.8%) died of cardiac causes; whereas, in 5 patients with bradyarrhythmias, 4 had been implanted with pacemakers and 3 (60.0%) died of cardiac causes. Furthermore, the age at the onset of cardiac symptoms in patients with any kind of conduction disturbance, except tachyarrhythmia, was 50.4 +/- 16.5 years (n = 25), which was significantly higher (p less than 0.02) than that of patients without conduction disturbances (37.7 +/- 19.3 years, n = 23). We concluded that bradyarrhythmias are not rare complications in patients with dilated cardiomyopathy, and the mortality rate tends to be higher in patients with bradyarrhythmias than in those without them. Furthermore, the risks of conduction disturbances and bradyarrhythmias were higher in the elderly patients.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009200 Myocardial Contraction Contractile activity of the MYOCARDIUM. Heart Contractility,Inotropism, Cardiac,Cardiac Inotropism,Cardiac Inotropisms,Contractilities, Heart,Contractility, Heart,Contraction, Myocardial,Contractions, Myocardial,Heart Contractilities,Inotropisms, Cardiac,Myocardial Contractions
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D001919 Bradycardia Cardiac arrhythmias that are characterized by excessively slow HEART RATE, usually below 50 beats per minute in human adults. They can be classified broadly into SINOATRIAL NODE dysfunction and ATRIOVENTRICULAR BLOCK. Bradyarrhythmia,Bradyarrhythmias,Bradycardias
D002311 Cardiomyopathy, Dilated A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein. Cardiomyopathy, Congestive,Congestive Cardiomyopathy,Dilated Cardiomyopathy,Cardiomyopathy, Dilated, 1a,Cardiomyopathy, Dilated, Autosomal Recessive,Cardiomyopathy, Dilated, CMD1A,Cardiomyopathy, Dilated, LMNA,Cardiomyopathy, Dilated, With Conduction Defect 1,Cardiomyopathy, Dilated, with Conduction Deffect1,Cardiomyopathy, Familial Idiopathic,Cardiomyopathy, Idiopathic Dilated,Cardiomyopathies, Congestive,Cardiomyopathies, Dilated,Cardiomyopathies, Familial Idiopathic,Cardiomyopathies, Idiopathic Dilated,Congestive Cardiomyopathies,Dilated Cardiomyopathies,Dilated Cardiomyopathies, Idiopathic,Dilated Cardiomyopathy, Idiopathic,Familial Idiopathic Cardiomyopathies,Familial Idiopathic Cardiomyopathy,Idiopathic Cardiomyopathies, Familial,Idiopathic Cardiomyopathy, Familial,Idiopathic Dilated Cardiomyopathies,Idiopathic Dilated Cardiomyopathy
D005260 Female Females
D006339 Heart Rate The number of times the HEART VENTRICLES contract per unit of time, usually per minute. Cardiac Rate,Chronotropism, Cardiac,Heart Rate Control,Heartbeat,Pulse Rate,Cardiac Chronotropy,Cardiac Chronotropism,Cardiac Rates,Chronotropy, Cardiac,Control, Heart Rate,Heart Rates,Heartbeats,Pulse Rates,Rate Control, Heart,Rate, Cardiac,Rate, Heart,Rate, Pulse
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

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