| D008407 |
Mast Cells |
Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR. |
Basophils, Tissue,Basophil, Tissue,Cell, Mast,Cells, Mast,Mast Cell,Tissue Basophil,Tissue Basophils |
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| D008875 |
Middle Aged |
An adult aged 45 - 64 years. |
Middle Age |
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| D011537 |
Pruritus |
An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief. |
Itching,Pruritis |
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| D011701 |
PUVA Therapy |
Photochemotherapy using PSORALENS as the photosensitizing agent and ultraviolet light type A (UVA). |
Psoralen Ultraviolet A Therapy,Therapy, PUVA,PUVA Therapies,Therapies, PUVA |
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| D005260 |
Female |
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Females |
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| D006634 |
Histamine H1 Antagonists |
Drugs that selectively bind to but do not activate histamine H1 receptors, thereby blocking the actions of endogenous histamine. Included here are the classical antihistaminics that antagonize or prevent the action of histamine mainly in immediate hypersensitivity. They act in the bronchi, capillaries, and some other smooth muscles, and are used to prevent or allay motion sickness, seasonal rhinitis, and allergic dermatitis and to induce somnolence. The effects of blocking central nervous system H1 receptors are not as well understood. |
Antihistamines, Classical,Antihistaminics, Classical,Antihistaminics, H1,Histamine H1 Antagonist,Histamine H1 Receptor Antagonist,Histamine H1 Receptor Antagonists,Histamine H1 Receptor Blockaders,Antagonists, Histamine H1,Antagonists, Histamine H1 Receptor,Antihistamines, Sedating,Blockaders, Histamine H1 Receptor,First Generation H1 Antagonists,H1 Receptor Blockaders,Histamine H1 Blockers,Receptor Blockaders, H1,Antagonist, Histamine H1,Classical Antihistamines,Classical Antihistaminics,H1 Antagonist, Histamine,H1 Antagonists, Histamine,H1 Antihistaminics,Sedating Antihistamines |
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| D006801 |
Humans |
Members of the species Homo sapiens. |
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man |
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| D012867 |
Skin |
The outer covering of the body that protects it from the environment. It is composed of the DERMIS and the EPIDERMIS. |
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| D034701 |
Mastocytosis, Cutaneous |
Skin lesions due to abnormal infiltration of MAST CELLS. Cutaneous mastocytosis is confined to the skin without the involvement of other tissues or organs, and is mostly found in children. The three major variants are: URTICARIA PIGMENTOSA; diffuse cutaneous mastocytosis; and SOLITARY MASTOCYTOMA OF SKIN. |
Cutaneous Mastocytosis,Mastocytosis, Bullous,Mastocytosis, Diffuse Cutaneous,Skin Mastocytosis,Bullous Mastocytoses,Bullous Mastocytosis,Cutaneous Mastocytoses,Cutaneous Mastocytoses, Diffuse,Cutaneous Mastocytosis, Diffuse,Mastocytoses, Bullous,Mastocytoses, Cutaneous,Mastocytoses, Skin,Mastocytosis, Skin,Skin Mastocytoses |
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