| D008967 |
Molecular Biology |
A discipline concerned with studying biological phenomena in terms of the chemical and physical interactions of molecules. |
Biochemical Genetics,Biology, Molecular,Genetics, Biochemical,Genetics, Molecular,Molecular Genetics,Biochemical Genetic,Genetic, Biochemical,Genetic, Molecular,Molecular Genetic |
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| D010012 |
Osteogenesis |
The process of bone formation. Histogenesis of bone including ossification. |
Bone Formation,Ossification, Physiologic,Endochondral Ossification,Ossification,Ossification, Physiological,Osteoclastogenesis,Physiologic Ossification,Endochondral Ossifications,Ossification, Endochondral,Ossifications,Ossifications, Endochondral,Osteoclastogeneses,Physiological Ossification |
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| D001861 |
Bone Regeneration |
Renewal or repair of lost bone tissue. It excludes BONY CALLUS formed after BONE FRACTURES but not yet replaced by hard bone. |
Osteoconduction,Bone Regenerations,Regeneration, Bone,Regenerations, Bone |
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| D006801 |
Humans |
Members of the species Homo sapiens. |
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man |
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| D016207 |
Cytokines |
Non-antibody proteins secreted by inflammatory leukocytes and some non-leukocytic cells, that act as intercellular mediators. They differ from classical hormones in that they are produced by a number of tissue or cell types rather than by specialized glands. They generally act locally in a paracrine or autocrine rather than endocrine manner. |
Cytokine |
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| D016212 |
Transforming Growth Factor beta |
A factor synthesized in a wide variety of tissues. It acts synergistically with TGF-alpha in inducing phenotypic transformation and can also act as a negative autocrine growth factor. TGF-beta has a potential role in embryonal development, cellular differentiation, hormone secretion, and immune function. TGF-beta is found mostly as homodimer forms of separate gene products TGF-beta1, TGF-beta2 or TGF-beta3. Heterodimers composed of TGF-beta1 and 2 (TGF-beta1.2) or of TGF-beta2 and 3 (TGF-beta2.3) have been isolated. The TGF-beta proteins are synthesized as precursor proteins. |
Bone-Derived Transforming Growth Factor,Platelet Transforming Growth Factor,TGF-beta,Milk Growth Factor,TGFbeta,Bone Derived Transforming Growth Factor,Factor, Milk Growth,Growth Factor, Milk |
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| D017102 |
Fracture Healing |
The physiological restoration of bone tissue and function after a fracture. It includes BONY CALLUS formation and normal replacement of bone tissue. |
Fracture Healings,Healing, Fracture,Healings, Fracture |
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| D018919 |
Neovascularization, Physiologic |
The development of new BLOOD VESSELS during the restoration of BLOOD CIRCULATION during the healing process. |
Angiogenesis, Physiologic,Angiogenesis, Physiological,Neovascularization, Physiological,Physiologic Angiogenesis,Physiologic Neovascularization,Physiological Angiogenesis,Physiological Neovascularization |
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| D019485 |
Bone Morphogenetic Proteins |
Bone-growth regulatory factors that are members of the transforming growth factor-beta superfamily of proteins. They are synthesized as large precursor molecules which are cleaved by proteolytic enzymes. The active form can consist of a dimer of two identical proteins or a heterodimer of two related bone morphogenetic proteins. |
Bone Morphogenetic Protein,Morphogenetic Protein, Bone,Morphogenetic Proteins, Bone |
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| D019857 |
Osteogenesis, Distraction |
Bone lengthening by gradual mechanical distraction. An external fixation device produces the distraction across the bone plate. The technique was originally applied to long bones but in recent years the method has been adapted for use with mandibular implants in maxillofacial surgery. |
Callotasis,Distraction Osteogenesis,Callotases,Distraction Osteogeneses,Osteogeneses, Distraction |
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