Biomaterial Database

[Personality characteristics as a prognostic factor in using antidepressive drugs in endogenous depression]. 1991

E Habrat, and W Walecka

II Kliniki Psychiatrycznej Instytutu Psychiatrii i Neurologii.

The study aimed to test usefulness of personality patterns for prediction of efficacy of antidepressant drugs in patients with endogenous depression. No association between a positive response to treatment and such personality traits as neuroticism, extraversion, nervous system reactivity or MMPI clinical scales profile was demonstrated. A positive response to the pharmacological treatment was significantly more frequently observed in persons characterized by a capability to control expression of mental symptoms (subscale Cn in MMPI). A lack of response to treatment was more frequently observed in persons demonstrating high scores in lie scales of MMPI and MPI and characterized by higher score in Re (responsibility) subscale of MMPI.

UI	MeSH Term	Description	Entries
D010551	Personality	Behavior-response patterns that characterize the individual.	Personalities
D010556	Personality Tests	Standardized objective tests designed to facilitate the evaluation of personality.	Personality Test,Test, Personality,Tests, Personality
D011379	Prognosis	A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.	Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D012074	Remission Induction	Therapeutic act or process that initiates a response to a complete or partial remission level.	Induction of Remission,Induction, Remission,Inductions, Remission,Remission Inductions
D003866	Depressive Disorder	An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.	Depression, Endogenous,Depression, Neurotic,Depression, Unipolar,Depressive Syndrome,Melancholia,Neurosis, Depressive,Unipolar Depression,Depressions, Endogenous,Depressions, Neurotic,Depressions, Unipolar,Depressive Disorders,Depressive Neuroses,Depressive Neurosis,Depressive Syndromes,Disorder, Depressive,Disorders, Depressive,Endogenous Depression,Endogenous Depressions,Melancholias,Neuroses, Depressive,Neurotic Depression,Neurotic Depressions,Syndrome, Depressive,Syndromes, Depressive,Unipolar Depressions
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000928	Antidepressive Agents	Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems.	Antidepressant,Antidepressant Drug,Antidepressant Medication,Antidepressants,Antidepressive Agent,Thymoanaleptic,Thymoanaleptics,Thymoleptic,Thymoleptics,Antidepressant Drugs,Agent, Antidepressive,Drug, Antidepressant,Medication, Antidepressant