BIOMAT Database Logo BIOMAT Database Logo

[Antimicrobial sensitivity of 402 strains of Neisseria gonorrhoeae isolated in 7 Spanish cities]. 1991

E J Perea, and J L García-López, and R Martín, and M Calmet, and R Cisterna, and V Estébanez, and J A Vázquez, and F Martín Luengo, and A Altuna, and C Merino
Departamento de Microbiología, Facultad de Medicina de Sevilla.

To study N. gonorrhoeae resistance in Spain. We evaluate 402 strains consecutively isolated in 7 Spanish cities (Barcelona, Bilbao, Madrid, Murcia, Seville, Valencia and Valladolid). The MIC to 9 antimicrobial agents was determined by agar-dilution (DST) method. We found a high incidence (15.7%) of penicillinase producer strains (NGPP). Most (53.3%) of all non-NGPP strains showed reduced sensitivity to penicillin and 1.5% of the strains had chromosomally mediated resistance. All NGPP strains and 90% of non-NGPP strains showed reduced sensitivity to tetracycline (MIC greater than 0.23 mg/l). We did not found any strain with high-level tetracycline resistance. MIC90 for the other drugs tested were: erythromycin, 0.125 mg/l; spectinomycin, 16 mg/l; cefoxitin, 2 mg/l; cefuroxime 0.06 mg/l; ceftriaxone 0.0037 mg/l; ofloxacin 0.06 mg/l and ciprofloxacin, 0.0018 mg/l. NGPP are very prevalent in Spain. Most of these strains had chromosomally mediated resistance to penicillin and tetracycline. We did not found resistance to other antimicrobial agents.

UI MeSH Term Description Entries
D009344 Neisseria gonorrhoeae A species of gram-negative, aerobic bacteria primarily found in purulent venereal discharges. It is the causative agent of GONORRHEA. Diplococcus gonorrhoeae,Gonococcus,Gonococcus neisseri,Merismopedia gonorrhoeae,Micrococcus der gonorrhoe,Micrococcus gonococcus,Micrococcus gonorrhoeae
D010405 Penicillinase A beta-lactamase preferentially cleaving penicillins. (Dorland, 28th ed) EC 3.5.2.-. beta-Lactamase I,AER-I beta-Lactamase,Benzylpenicillinase,Carbenicillinase,Exopenicillinase,beta Lactamase III,beta Lactamase RP4,gamma-Penicillinase,AER I beta Lactamase,Lactamase RP4, beta,beta Lactamase I,beta-Lactamase, AER-I,gamma Penicillinase
D011446 Prospective Studies Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group. Prospective Study,Studies, Prospective,Study, Prospective
D004352 Drug Resistance, Microbial The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS). Antibiotic Resistance,Antibiotic Resistance, Microbial,Antimicrobial Resistance, Drug,Antimicrobial Drug Resistance,Antimicrobial Drug Resistances,Antimicrobial Resistances, Drug,Drug Antimicrobial Resistance,Drug Antimicrobial Resistances,Drug Resistances, Microbial,Resistance, Antibiotic,Resistance, Drug Antimicrobial,Resistances, Drug Antimicrobial
D006069 Gonorrhea Acute infectious disease characterized by primary invasion of the urogenital tract. The etiologic agent, NEISSERIA GONORRHOEAE, was isolated by Neisser in 1879. Neisseria gonorrhoeae Infection
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001426 Bacterial Proteins Proteins found in any species of bacterium. Bacterial Gene Products,Bacterial Gene Proteins,Gene Products, Bacterial,Bacterial Gene Product,Bacterial Gene Protein,Bacterial Protein,Gene Product, Bacterial,Gene Protein, Bacterial,Gene Proteins, Bacterial,Protein, Bacterial,Proteins, Bacterial
D013030 Spain Country located between France on the northeast and Portugal on the west and bordered by the Atlantic Ocean and the Mediterranean Sea. The capital is Madrid. Balearic Islands,Canary Islands
D014505 Urban Population The inhabitants of a city or town, including metropolitan areas and suburban areas. Urban Residence,Urban Spatial Distribution,Distribution, Urban Spatial,Distributions, Urban Spatial,Population, Urban,Populations, Urban,Residence, Urban,Urban Populations,Urban Residences,Urban Spatial Distributions

Related Publications

E J Perea, and J L García-López, and R Martín, and M Calmet, and R Cisterna, and V Estébanez, and J A Vázquez, and F Martín Luengo, and A Altuna, and C Merino
Antimicrobial susceptibilities of Neisseria gonorrhoeae strains isolated in Java, Indonesia.
January 2003, Sexually transmitted diseases,
E J Perea, and J L García-López, and R Martín, and M Calmet, and R Cisterna, and V Estébanez, and J A Vázquez, and F Martín Luengo, and A Altuna, and C Merino
Antimicrobial susceptibilities of Neisseria gonorrhoeae strains isolated in Surabaya, Indonesia.
November 1994, Antimicrobial agents and chemotherapy,
E J Perea, and J L García-López, and R Martín, and M Calmet, and R Cisterna, and V Estébanez, and J A Vázquez, and F Martín Luengo, and A Altuna, and C Merino
[Antimicrobial sensitivity, auxotype, serotype and plasmid analysis of 75 strains of Neisseria gonorrhoeae isolated in Barcelona].
February 1990, Medicina clinica,
E J Perea, and J L García-López, and R Martín, and M Calmet, and R Cisterna, and V Estébanez, and J A Vázquez, and F Martín Luengo, and A Altuna, and C Merino
Antimicrobial susceptibility of Neisseria gonorrhoeae strains isolated in Guangzhou, China, 1996-2001.
October 2003, Sexually transmitted infections,
E J Perea, and J L García-López, and R Martín, and M Calmet, and R Cisterna, and V Estébanez, and J A Vázquez, and F Martín Luengo, and A Altuna, and C Merino
[Antimicrobial resistance of Neisseria gonorrhoeae strains isolated from sex workers in Ankara].
January 2006, Mikrobiyoloji bulteni,
E J Perea, and J L García-López, and R Martín, and M Calmet, and R Cisterna, and V Estébanez, and J A Vázquez, and F Martín Luengo, and A Altuna, and C Merino
In Vitro Penicillin Sensitivity of Neisseria Gonorrhoeae Strains Isolated in Pune (India).
January 1980, Indian journal of dermatology, venereology and leprology,
E J Perea, and J L García-López, and R Martín, and M Calmet, and R Cisterna, and V Estébanez, and J A Vázquez, and F Martín Luengo, and A Altuna, and C Merino
Antimicrobial susceptibility of Neisseria gonorrhoeae strains isolated in Nuuk, Greenland during 1998-1999.
December 2002, International journal of STD & AIDS,
E J Perea, and J L García-López, and R Martín, and M Calmet, and R Cisterna, and V Estébanez, and J A Vázquez, and F Martín Luengo, and A Altuna, and C Merino
Antimicrobial susceptibility testing, auxotyping, and serotyping of Neisseria gonorrhoeae strains isolated in India.
March 2012, Sexually transmitted diseases,
E J Perea, and J L García-López, and R Martín, and M Calmet, and R Cisterna, and V Estébanez, and J A Vázquez, and F Martín Luengo, and A Altuna, and C Merino
[Neisseria gonorrhoeae. Comparative study of sensitivity to antibiotics in strains isolated in 1965].
October 1966, Ceskoslovenska dermatologie,
E J Perea, and J L García-López, and R Martín, and M Calmet, and R Cisterna, and V Estébanez, and J A Vázquez, and F Martín Luengo, and A Altuna, and C Merino
Survey on antibiotic sensitivity of Neisseria gonorrhoeae strains isolated in China, 1987-1992.
January 1994, Sexually transmitted diseases,
Copied contents to your clipboard!