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Studies were made on the effects of alpha-amanitin, cycloheximide, and thioacetamide on synthesis and content of low molecular weight nuclear RNA. Cycloheximide, an inhibitor of protein synthesis and the synthesis of 45S pre-rRNA and 5S RNA, also inhibited synthesis of nuclear U1 and U3 RNAs. alpha-Amanitin, an inhibited the synthesis of U1 and U2 low molecular weight nuclear RNA. Thioacetamide, which induces nucleolar hypertrophy and increased nucleolar RNA polymerase activity, markedly increased synthesis of 5.8S RNA and U3 RNA. These results show that syntheses of individual low molecular weight nuclear (LMWN) RNAs are controlled by different regulatory mechanisms. In particular, there appears to be a specific relationship between U3 RNA and functional states of the nucleolus.
T S Ro-Choi, and
N B Raj, and
L M Pike, and
H Busch
February 1979,
Journal of virology,
T S Ro-Choi, and
N B Raj, and
L M Pike, and
H Busch
August 1972,
Nature: New biology,
T S Ro-Choi, and
N B Raj, and
L M Pike, and
H Busch
November 1984,
Endocrinology,
T S Ro-Choi, and
N B Raj, and
L M Pike, and
H Busch
March 1978,
FEBS letters,
T S Ro-Choi, and
N B Raj, and
L M Pike, and
H Busch
March 1991,
Molecular reproduction and development,
T S Ro-Choi, and
N B Raj, and
L M Pike, and
H Busch
June 1973,
European journal of biochemistry,
T S Ro-Choi, and
N B Raj, and
L M Pike, and
H Busch
January 1978,
Experimental cell research,
T S Ro-Choi, and
N B Raj, and
L M Pike, and
H Busch
January 1979,
Nucleic acids research,
T S Ro-Choi, and
N B Raj, and
L M Pike, and
H Busch
October 1970,
Science (New York, N.Y.),
T S Ro-Choi, and
N B Raj, and
L M Pike, and
H Busch
January 1984,
Molekuliarnaia biologiia,
