The treatment of bifurcation coronary artery disease is a common challenge facing the interventional cardiologist. There have been major advances in techniques as well as more widespread use of drug-eluting stents; both appear to have contributed to the realization of single-digit target lesion revascularization rates as well as improvement in short-term complications such as stent thrombosis. Adequate treatment of the side branch ostium, the site most frequently described as being susceptible to restenosis, has become the focus of newer bifurcation techniques as well as dedicated devices for the treatment of this complex lesion subset. Since main branch reintervention rates are sufficiently low and silent restenosis of the side branch ostium is an all-too-common finding, there is no clear consensus on the optimal treatment strategy for bifurcation coronary disease. The following is a comprehensive review of those commonly used techniques as well as dedicated devices currently under development for the treatment of bifurcation coronary artery disease.