Biomaterial Database

Tonic pupil and Czarnecki's sign following third nerve palsy. 1991

T A Cox, and R A Goldberg, and J Rootman

Department of Ophthalmology, University of British Columbia, Vancouver, Canada.

A 71-year-old woman developed abnormal pupillary function in one eye after a third nerve palsy. Stimulation with light caused segmental constriction of the pupil, the near reflex was normal, and gaze upward elicited constriction of portions of the sphincter that were unreactive to light. This combination of findings has not been reported previously. We believe that this case supports the idea that a tonic pupil can be caused by aberrant reinnervation of the ciliary ganglion.

UI	MeSH Term	Description	Entries
D008027	Light	That portion of the electromagnetic spectrum in the visible, ultraviolet, and infrared range.	Light, Visible,Photoradiation,Radiation, Visible,Visible Radiation,Photoradiations,Radiations, Visible,Visible Light,Visible Radiations
D011680	Pupil	The aperture in the iris through which light passes.	Pupils
D012025	Reflex, Pupillary	Constriction of the pupil in response to light stimulation of the retina. It refers also to any reflex involving the iris, with resultant alteration of the diameter of the pupil. (Cline et al., Dictionary of Visual Science, 4th ed)	Pupillary Reflex
D005133	Eye Movements	Voluntary or reflex-controlled movements of the eye.	Eye Movement,Movement, Eye,Movements, Eye
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000368	Aged	A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available.	Elderly
D015840	Oculomotor Nerve Diseases	Diseases of the oculomotor nerve or nucleus that result in weakness or paralysis of the superior rectus, inferior rectus, medial rectus, inferior oblique, or levator palpebrae muscles, or impaired parasympathetic innervation to the pupil. With a complete oculomotor palsy, the eyelid will be paralyzed, the eye will be in an abducted and inferior position, and the pupil will be markedly dilated. Commonly associated conditions include neoplasms, CRANIOCEREBRAL TRAUMA, ischemia (especially in association with DIABETES MELLITUS), and aneurysmal compression. (From Adams et al., Principles of Neurology, 6th ed, p270)	Cranial Nerve III Diseases,Third-Nerve Palsy,Oculomotor Nerve Disorders,Oculomotor Nerve Palsy,Oculomotor Nerve Paralysis,Oculomotor Neuropathy,Partial Third-Nerve Palsy,Third Cranial Nerve Diseases,Third-Nerve Paralysis,Total Third-Nerve Palsy,Nerve Disease, Oculomotor,Nerve Disorder, Oculomotor,Nerve Palsy, Oculomotor,Nerve Paralysis, Oculomotor,Neuropathy, Oculomotor,Oculomotor Nerve Disease,Oculomotor Nerve Disorder,Oculomotor Nerve Palsies,Oculomotor Nerve Paralyses,Oculomotor Neuropathies,Palsy, Oculomotor Nerve,Palsy, Partial Third-Nerve,Palsy, Third-Nerve,Palsy, Total Third-Nerve,Paralysis, Oculomotor Nerve,Paralysis, Third-Nerve,Partial Third Nerve Palsy,Partial Third-Nerve Palsies,Third Nerve Palsy,Third Nerve Paralysis,Third-Nerve Palsies,Third-Nerve Palsies, Partial,Third-Nerve Palsy, Partial,Third-Nerve Palsy, Total,Third-Nerve Paralyses,Total Third Nerve Palsy,Total Third-Nerve Palsies
D015845	Tonic Pupil	A pupillary abnormality characterized by a poor pupillary light reaction, reduced accommodation, iris sector palsies, an enhanced pupillary response to near effort that results in a prolonged, "tonic" constriction, and slow pupillary redilation. This condition is associated with injury to the postganglionic parasympathetic innervation to the pupil. (From Miller et al., Clinical Neuro-Ophthalmology, 4th ed, pp492-500)	Adie's Pupil,Pupil, Tonic,Adie Pupil,Myotonic Pupil,Pupillotonia,Tonic Pupil, Local,Tonic Pupil, Neuropathic,Adies Pupil,Myotonic Pupils,Neuropathic Tonic Pupil,Neuropathic Tonic Pupils,Pupil, Adie,Pupil, Adie's,Pupil, Local Tonic,Pupil, Myotonic,Pupil, Neuropathic Tonic,Pupillotonias,Pupils, Adie's,Pupils, Local Tonic,Pupils, Myotonic,Pupils, Neuropathic Tonic,Pupils, Tonic,Tonic Pupils,Tonic Pupils, Local,Tonic Pupils, Neuropathic