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The cell toxicity, hemolytic and clastogenic activity were examined in various kinds of asbestos and some asbestos substitutes with reference to the their mineralogical and physicochemical characteristics. There were thirty-five fibrous and non-fibrous samples including UICC chrysotile, size-selected samples of UICC chrysotile, chrysotile altered by heating and grinding, Yamabe (Japan) chrysotile with long and short fibers, Coalinga (U.S. A.) chrysotile with short fibers, UICC crocidolite, amosite, and 19 non-asbestos samples such as, glass fibers, calcium silicates, sepiolites and some clay minerals. The cell toxicity and the hemolytic and clastogenic activity of asbestos were the strongest for chrysotile among all of the asbestos samples tested, and their strengths varied with fiber length and with the conditions of grinding and heating. These cellular effects of Yamabe chrysotile with long fibers and size-selected UICC chrysotile with long fibers were stronger than those of chrysotile of the same origin but with short fibers. These effects were weaker in chrysotile altered by heating and grinding. Among the asbestos substitutes, the cell toxicity, hemolytic and clastogenic activities of thin glass fibers were more marked than those of thick glass fibers. The four types of sepiolite were strongly hemolytic, but their cell toxicity and clastogenicity varied according to their grade of crystallinity and/or fiber size. These effects of calcium silicates and some clay minerals were generally low but varied with mineral species. In general, the cell toxicity, hemolytic and clastogenic activities of the asbestos substitutes tested here were mild compared with those of asbestos.
K Koshi, and
N Kohyama, and
T Myojo, and
K Fukuda
January 1995,
Voprosy meditsinskoi khimii,
K Koshi, and
N Kohyama, and
T Myojo, and
K Fukuda
January 1978,
Annales pharmaceutiques francaises,
K Koshi, and
N Kohyama, and
T Myojo, and
K Fukuda
January 1968,
La Medicina del lavoro,
K Koshi, and
N Kohyama, and
T Myojo, and
K Fukuda
February 1977,
Environmental research,
K Koshi, and
N Kohyama, and
T Myojo, and
K Fukuda
January 1992,
Medycyna pracy,
K Koshi, and
N Kohyama, and
T Myojo, and
K Fukuda
August 1999,
Environmental health perspectives,
K Koshi, and
N Kohyama, and
T Myojo, and
K Fukuda
March 2018,
Journal of natural products,
K Koshi, and
N Kohyama, and
T Myojo, and
K Fukuda
December 1999,
Environmental health perspectives,
K Koshi, and
N Kohyama, and
T Myojo, and
K Fukuda
June 1983,
Nihon eiseigaku zasshi. Japanese journal of hygiene,
K Koshi, and
N Kohyama, and
T Myojo, and
K Fukuda
January 1964,
Internationale Zeitschrift fur Vitaminforschung. International journal of vitamin research. Journal international de vitaminologie,
