Occlusal tooth wear in male F344/N rats with aging. 2009

Kazutoshi Nishijima, and Sachi Kuwahara, and Tamio Ohno, and Osamu Miyaishi, and Yoshitake Ito, and Yasunori Sumi, and Shin Tanaka
Animal Facility for Aging Research, National Institute for Longevity Sciences, National Center for Geriatrics and Gerontology, Morioka-cho, Obu, Japan. kazz@nils.go.jp

With the aim of clarifying the aging properties of an animal model, the progress of occlusal tooth wear (OTW) of molars in male F344/N rats was monitored. Dried maxilla and mandible specimens from 61 male F344/N rats, aged 7 to >30 months, were used. The levels of OTW of all molars were monitored with aging. The cuspis dentis of molar teeth were worn out by 7 months (M) of age, and the occlusal surface became flat. As for each molar tooth (M(1-3), numbered in accordance with its position), OTW of M(1) was more severe in the lower than in the upper jaw, whereas M(3) was more severe in the upper than the lower jaw. OTW of M(2) in both the upper and the lower jaws progressed rapidly after 27M. OTW in male F344/N rats progressed faster than in females. However, when compensated for life span, both genders had similar profiles in OTW progress with aging. This study suggested that male rats were more convenient than females as a model for gerodontological research because of the earlier course of OTW progress.

UI MeSH Term Description Entries
D008297 Male Males
D008954 Models, Biological Theoretical representations that simulate the behavior or activity of biological processes or diseases. For disease models in living animals, DISEASE MODELS, ANIMAL is available. Biological models include the use of mathematical equations, computers, and other electronic equipment. Biological Model,Biological Models,Model, Biological,Models, Biologic,Biologic Model,Biologic Models,Model, Biologic
D008963 Molar The most posterior teeth on either side of the jaw, totaling eight in the deciduous dentition (2 on each side, upper and lower), and usually 12 in the permanent dentition (three on each side, upper and lower). They are grinding teeth, having large crowns and broad chewing surfaces. (Jablonski, Dictionary of Dentistry, 1992, p821) Molars
D011916 Rats, Inbred F344 An inbred strain of rat that is used for general BIOMEDICAL RESEARCH purposes. Fischer Rats,Rats, Inbred CDF,Rats, Inbred Fischer 344,Rats, F344,Rats, Inbred Fisher 344,CDF Rat, Inbred,CDF Rats, Inbred,F344 Rat,F344 Rat, Inbred,F344 Rats,F344 Rats, Inbred,Inbred CDF Rat,Inbred CDF Rats,Inbred F344 Rat,Inbred F344 Rats,Rat, F344,Rat, Inbred CDF,Rat, Inbred F344,Rats, Fischer
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000375 Aging The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time. Senescence,Aging, Biological,Biological Aging
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012737 Sex Factors Maleness or femaleness as a constituent element or influence contributing to the production of a result. It may be applicable to the cause or effect of a circumstance. It is used with human or animal concepts but should be differentiated from SEX CHARACTERISTICS, anatomical or physiological manifestations of sex, and from SEX DISTRIBUTION, the number of males and females in given circumstances. Factor, Sex,Factors, Sex,Sex Factor
D051381 Rats The common name for the genus Rattus. Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus
D019217 Tooth Attrition The wearing away of a tooth as a result of tooth-to-tooth contact, as in mastication, occurring only on the occlusal, incisal, and proximal surfaces. It is chiefly associated with aging. It is differentiated from TOOTH ABRASION (the pathologic wearing away of the tooth substance by friction, as brushing, bruxism, clenching, and other mechanical causes) and from TOOTH EROSION (the loss of substance caused by chemical action without bacterial action). (Jablonski, Dictionary of Dentistry, 1992, p86) Dental Attrition,Attrition, Dental,Occlusal Wear,Attrition, Tooth,Dental Attritions,Occlusal Wears,Wear, Occlusal,Wears, Occlusal

Related Publications

Kazutoshi Nishijima, and Sachi Kuwahara, and Tamio Ohno, and Osamu Miyaishi, and Yoshitake Ito, and Yasunori Sumi, and Shin Tanaka
January 1987, The Journal of prosthetic dentistry,
Kazutoshi Nishijima, and Sachi Kuwahara, and Tamio Ohno, and Osamu Miyaishi, and Yoshitake Ito, and Yasunori Sumi, and Shin Tanaka
September 1983, Les Cahiers de prothese,
Kazutoshi Nishijima, and Sachi Kuwahara, and Tamio Ohno, and Osamu Miyaishi, and Yoshitake Ito, and Yasunori Sumi, and Shin Tanaka
March 2000, Journal of forensic sciences,
Kazutoshi Nishijima, and Sachi Kuwahara, and Tamio Ohno, and Osamu Miyaishi, and Yoshitake Ito, and Yasunori Sumi, and Shin Tanaka
June 2019, Australian dental journal,
Kazutoshi Nishijima, and Sachi Kuwahara, and Tamio Ohno, and Osamu Miyaishi, and Yoshitake Ito, and Yasunori Sumi, and Shin Tanaka
June 2014, BMC oral health,
Kazutoshi Nishijima, and Sachi Kuwahara, and Tamio Ohno, and Osamu Miyaishi, and Yoshitake Ito, and Yasunori Sumi, and Shin Tanaka
November 1986, Toxicology,
Kazutoshi Nishijima, and Sachi Kuwahara, and Tamio Ohno, and Osamu Miyaishi, and Yoshitake Ito, and Yasunori Sumi, and Shin Tanaka
February 2014, Journal of oral rehabilitation,
Kazutoshi Nishijima, and Sachi Kuwahara, and Tamio Ohno, and Osamu Miyaishi, and Yoshitake Ito, and Yasunori Sumi, and Shin Tanaka
September 1999, The Journal of prosthetic dentistry,
Kazutoshi Nishijima, and Sachi Kuwahara, and Tamio Ohno, and Osamu Miyaishi, and Yoshitake Ito, and Yasunori Sumi, and Shin Tanaka
March 1995, American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics,
Kazutoshi Nishijima, and Sachi Kuwahara, and Tamio Ohno, and Osamu Miyaishi, and Yoshitake Ito, and Yasunori Sumi, and Shin Tanaka
January 1992, Swedish dental journal. Supplement,
Copied contents to your clipboard!