-transparent.png){kind=logo}
A group of 124 children undergoing open-heart surgery was followed prospectively in order to estimate the risk of cytomegalovirus (CMV) infection due to transfused blood.Ninety-three patients (75%) had complement fixation (CF) titers of < 1:4 against CMV on admission. Of this seronegative subgroup, nine patients (9.7%) subsequently became infected with CMV. All nine showed seroconversion, and six were viruric 12-14 weeks after surgery. Comparative seroepidemiological studies of the hospital population showed that in the age ranges studied (3-16 yr), the infections seen in the study group represented a significant excess over expectation. This infection rate was consistent with a model of transmission by blood transfusion with a risk of 2.7% per unit but not proven.Thirty-one patients had CF antibody to CMV on admission. CMV was isolated from 14% of urines of seropositive children both before and after surgery, but only two patients showed CF antibody rises to CMV. Thus the frequency of CMV infection associated with open-heart surgery and transfusion could not be calculated in the seropositive subgroup.CMV infection was not related to the primary diagnosis or to Down's syndrome.
J A Armstrong, and
G C Tarr, and
L A Youngblood, and
J N Dowling, and
A R Saslow, and
J P Lucas, and
M Ho
January 1968,
Scandinavian journal of thoracic and cardiovascular surgery,
J A Armstrong, and
G C Tarr, and
L A Youngblood, and
J N Dowling, and
A R Saslow, and
J P Lucas, and
M Ho
January 1985,
Acta medica Scandinavica,
J A Armstrong, and
G C Tarr, and
L A Youngblood, and
J N Dowling, and
A R Saslow, and
J P Lucas, and
M Ho
October 1981,
JAMA,
J A Armstrong, and
G C Tarr, and
L A Youngblood, and
J N Dowling, and
A R Saslow, and
J P Lucas, and
M Ho
April 1987,
European heart journal,
J A Armstrong, and
G C Tarr, and
L A Youngblood, and
J N Dowling, and
A R Saslow, and
J P Lucas, and
M Ho
March 1978,
[Kango gijutsu] : [Nursing technique],
J A Armstrong, and
G C Tarr, and
L A Youngblood, and
J N Dowling, and
A R Saslow, and
J P Lucas, and
M Ho
January 1973,
Surgical forum,
J A Armstrong, and
G C Tarr, and
L A Youngblood, and
J N Dowling, and
A R Saslow, and
J P Lucas, and
M Ho
February 1990,
Blood,
J A Armstrong, and
G C Tarr, and
L A Youngblood, and
J N Dowling, and
A R Saslow, and
J P Lucas, and
M Ho
November 1968,
The American journal of cardiology,
J A Armstrong, and
G C Tarr, and
L A Youngblood, and
J N Dowling, and
A R Saslow, and
J P Lucas, and
M Ho
March 1972,
Thorax,
J A Armstrong, and
G C Tarr, and
L A Youngblood, and
J N Dowling, and
A R Saslow, and
J P Lucas, and
M Ho
March 1978,
[Kango gijutsu] : [Nursing technique],
