Biomaterial Database

Contact allergens in registered chemical products. 1991

M A Flyvholm

Product Register Department, National Institute of Occupational Health, Copenhagen, Denmark.

A national database on chemical products (the Danish Product Register (PROBAS] was searched for products containing selected contact allergens. As of June 1990, a total of 47,400 products were registered in PROBAS. About 27,800 of these were fully computerized. A list of 43 allergens was established, based on the European standard patch test series, substances classified "May cause sensitization by skin contact", text books on contact dermatitis, and clinical experience. The number of products in which each of these allergens was registered varied from 30 to more than 1300. Formaldehyde was registered in all product categories included in the study. Benzyl alcohol, stearic acid, epoxy compounds, diethylenetriamine and butylated hydroxytoluene were registered in more than half of the product categories. Paints/lacquers and hardeners for two-component products (paints, glues, fillers, etc.), cleaning agents, binders, adhesives/glues and toiletries made up the most frequently registered product categories for the allergens listed. The possibilities and limitations of database information on chemical products are discussed.

UI	MeSH Term	Description	Entries
D009783	Dermatitis, Occupational	A recurrent contact dermatitis caused by substances found in the work place.	Occupational Dermatitis,Dermatosis, Industrial,Industrial Dermatosis,Dermatitides, Occupational,Dermatoses, Industrial,Industrial Dermatoses,Occupational Dermatitides
D002617	Chemical Industry	The aggregate enterprise of manufacturing and technically producing chemicals. (From Random House Unabridged Dictionary, 2d ed)	Industry, Chemical,Chemical Industries,Industries, Chemical
D003718	Denmark	A country in northern Europe, bordering the Baltic Sea and the North Sea. The capital is Copenhagen.	Faeroe Islands,Faroe Islands
D003877	Dermatitis, Contact	A type of acute or chronic skin reaction in which sensitivity is manifested by reactivity to materials or substances coming in contact with the skin. It may involve allergic or non-allergic mechanisms.	Contact Dermatitis,Dermatitis Venenata,Eczema, Contact,Hypersensitivity, Contact,Sensitivity, Contact,Contact Dermatitides,Contact Eczema,Contact Hypersensitivities,Contact Hypersensitivity,Contact Sensitivities,Contact Sensitivity,Dermatitides, Contact,Hypersensitivities, Contact,Sensitivities, Contact
D005060	Europe	The continent north of AFRICA, west of ASIA and east of the ATLANTIC OCEAN.	Northern Europe,Southern Europe,Western Europe
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000485	Allergens	Antigen-type substances that produce immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE).	Allergen
D016208	Databases, Factual	Extensive collections, reputedly complete, of facts and data garnered from material of a specialized subject area and made available for analysis and application. The collection can be automated by various contemporary methods for retrieval. The concept should be differentiated from DATABASES, BIBLIOGRAPHIC which is restricted to collections of bibliographic references.	Databanks, Factual,Data Banks, Factual,Data Bases, Factual,Data Bank, Factual,Data Base, Factual,Databank, Factual,Database, Factual,Factual Data Bank,Factual Data Banks,Factual Data Base,Factual Data Bases,Factual Databank,Factual Databanks,Factual Database,Factual Databases