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A jejunal biopsy specimen from an asymptomatic 35 year old man was studied because of a low serum titre of reticulin antibody and the finding of coeliac disease in his son. In this specimen villous structure was quite normal as was the total number of intraepithelial lymphocytes, but the number of gamma/delta T cell receptor bearing lymphocytes was 10 times higher than the mean in control subjects. Two years later a further biopsy specimen was obtained because of clinical symptoms and an increased titre of reticulin antibody. This specimen showed villous atrophy with crypt hyperplasia and increased infiltration of intraepithelial lymphocytes compatible with coeliac disease. A control biopsy specimen taken during gluten free diet showed normalisation of the villous architecture. Latent coeliac disease may be characterised by an increase in gamma/delta positive cells similar to that seen in established coeliac disease.
M Mäki, and
K Holm, and
P Collin, and
E Savilahti
July 1991,
Human pathology,
M Mäki, and
K Holm, and
P Collin, and
E Savilahti
June 1990,
The Journal of investigative dermatology,
M Mäki, and
K Holm, and
P Collin, and
E Savilahti
September 1991,
Gastroenterology,
M Mäki, and
K Holm, and
P Collin, and
E Savilahti
December 1990,
Pediatric research,
M Mäki, and
K Holm, and
P Collin, and
E Savilahti
August 1992,
Immunology,
M Mäki, and
K Holm, and
P Collin, and
E Savilahti
August 1993,
Lancet (London, England),
M Mäki, and
K Holm, and
P Collin, and
E Savilahti
November 1992,
Journal of the National Cancer Institute,
M Mäki, and
K Holm, and
P Collin, and
E Savilahti
January 1990,
The Journal of investigative dermatology,
M Mäki, and
K Holm, and
P Collin, and
E Savilahti
November 1990,
The Journal of investigative dermatology,
M Mäki, and
K Holm, and
P Collin, and
E Savilahti
November 1990,
Archives of disease in childhood,
