Biomaterial Database

RNA editing in kinetoplastid protozoa. 1991

K Stuart

Seattle Biomedical Research Institute, Washington.

RNA editing produces mature mRNAs by adding and removing uridines within the mitochondrial transcripts. The edited sequence appears to be specified by small complementary RNAs using a non-templated process that may have features resembling RNA splicing. The accumulation of edited mRNAs is developmentally regulated.

UI	MeSH Term	Description	Entries
D005786	Gene Expression Regulation	Any of the processes by which nuclear, cytoplasmic, or intercellular factors influence the differential control (induction or repression) of gene action at the level of transcription or translation.	Gene Action Regulation,Regulation of Gene Expression,Expression Regulation, Gene,Regulation, Gene Action,Regulation, Gene Expression
D005796	Genes	A category of nucleic acid sequences that function as units of heredity and which code for the basic instructions for the development, reproduction, and maintenance of organisms.	Cistron,Gene,Genetic Materials,Cistrons,Genetic Material,Material, Genetic,Materials, Genetic
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D012323	RNA Processing, Post-Transcriptional	Post-transcriptional biological modification of messenger, transfer, or ribosomal RNAs or their precursors. It includes cleavage, methylation, thiolation, isopentenylation, pseudouridine formation, conformational changes, and association with ribosomal protein.	Post-Transcriptional RNA Modification,RNA Processing,Post-Transcriptional RNA Processing,Posttranscriptional RNA Processing,RNA Processing, Post Transcriptional,RNA Processing, Posttranscriptional,Modification, Post-Transcriptional RNA,Modifications, Post-Transcriptional RNA,Post Transcriptional RNA Modification,Post Transcriptional RNA Processing,Post-Transcriptional RNA Modifications,Processing, Posttranscriptional RNA,Processing, RNA,RNA Modification, Post-Transcriptional,RNA Modifications, Post-Transcriptional
D016053	RNA, Protozoan	Ribonucleic acid in protozoa having regulatory and catalytic roles as well as involvement in protein synthesis.	Protozoan RNA
D016830	Kinetoplastida	An order of flagellate protozoa. Characteristics include the presence of one or two flagella arising from a depression in the cell body and a single mitochondrion that extends the length of the body.	Kinetoplastidas
D017394	RNA, Guide, Kinetoplastida	Small kinetoplastid mitochondrial RNA that plays a major role in RNA EDITING. These molecules form perfect hybrids with edited mRNA sequences and possess nucleotide sequences at their 5'-ends that are complementary to the sequences of the mRNA's immediately downstream of the pre-edited regions.	Guide RNA, Kinetoplastida,Kinetoplastid Guide RNA,Kinetoplastid gRNA,Kinetoplastida Guide RNA,Leishmania Guide RNA,RNA, Guide Kinetoplastids,RNA, Guide Leishmania,RNA, Guide Trypanosoma,RNA, Kinetoplastida Guide,Trypanosoma Guide RNA,Trypanosoma gRNA,gRNA, Kinetoplastid,gRNA, Trypanosoma,Guide Kinetoplastids RNA,Guide Leishmania RNA,Guide RNA, Kinetoplastid,Guide RNA, Leishmania,Guide RNA, Trypanosoma,Guide Trypanosoma RNA,Kinetoplastids RNA, Guide,Leishmania RNA, Guide,RNA, Kinetoplastid Guide,RNA, Leishmania Guide,RNA, Trypanosoma Guide,Trypanosoma RNA, Guide