Biomaterial Database

[Prognostic significance of perfusion defect and its extension in dilated cardiomyopathy: assessment with thallium-201 myocardial scintigraphy]. 1991

J Takata, and Y Doi, and Y Yonezawa, and M Akizawa, and T Ozawa

Department of Medicine and Geriatrics, Kochi Medical School.

To determine whether a change in the size of a scintigraphic perfusion defect is of prognostic significance in dilated cardiomyopathy (DCM), we performed thallium-201 myocardial scintigraphy twice for each of 13 patients with mean intervals of 45 +/- 18 months. Seven patients showed clinical deterioration (Group D) during the follow-up period of 58 +/- 22 months; whereas, 6 patients improved clinically as well as echocardiographically (LVDd < or = 5.5 cm and %FS > or = 20%) (Group I). 1. The initial scintigraphy showed that 3 patients had large defects (LD), 2 had multiple small defects (MSD) and 2 had no defects (NL) in Group D. Among 6 patients in Group I, one had LD, 3 had MSD and 2 had NL. 2. The second scintigraphy showed that in 5 patients in Group D, the defects were progressively enlarged and in the remaining 2 who had no defects at the initial scintigraphy, new defects developed (MSD). Among 6 patients in Group I, no patient had enlargement of defects. In 4 patients with defects (1LD, 3MSD), the sizes in their defects reduced. 3. At the initial study, all 7 patients in Group D fitted NYHA functional class III-IV; while, in Group I, 4 of the 6 patients fitted class III-IV and 2 patients class II. In the second study, all 7 patients in Group D remained in class III-IV; whereas, all 6 patients in Group I fitted class I-II. Five of the 7 patients in Group D died of heart failure after the second study.(ABSTRACT TRUNCATED AT 250 WORDS)

UI	MeSH Term	Description	Entries
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D011379	Prognosis	A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations.	Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D011877	Radionuclide Imaging	The production of an image obtained by cameras that detect the radioactive emissions of an injected radionuclide as it has distributed differentially throughout tissues in the body. The image obtained from a moving detector is called a scan, while the image obtained from a stationary camera device is called a scintiphotograph.	Gamma Camera Imaging,Radioisotope Scanning,Scanning, Radioisotope,Scintigraphy,Scintiphotography,Imaging, Gamma Camera,Imaging, Radionuclide
D002311	Cardiomyopathy, Dilated	A form of CARDIAC MUSCLE disease that is characterized by ventricular dilation, VENTRICULAR DYSFUNCTION, and HEART FAILURE. Risk factors include SMOKING; ALCOHOL DRINKING; HYPERTENSION; INFECTION; PREGNANCY; and mutations in the LMNA gene encoding LAMIN TYPE A, a NUCLEAR LAMINA protein.	Cardiomyopathy, Congestive,Congestive Cardiomyopathy,Dilated Cardiomyopathy,Cardiomyopathy, Dilated, 1a,Cardiomyopathy, Dilated, Autosomal Recessive,Cardiomyopathy, Dilated, CMD1A,Cardiomyopathy, Dilated, LMNA,Cardiomyopathy, Dilated, With Conduction Defect 1,Cardiomyopathy, Dilated, with Conduction Deffect1,Cardiomyopathy, Familial Idiopathic,Cardiomyopathy, Idiopathic Dilated,Cardiomyopathies, Congestive,Cardiomyopathies, Dilated,Cardiomyopathies, Familial Idiopathic,Cardiomyopathies, Idiopathic Dilated,Congestive Cardiomyopathies,Dilated Cardiomyopathies,Dilated Cardiomyopathies, Idiopathic,Dilated Cardiomyopathy, Idiopathic,Familial Idiopathic Cardiomyopathies,Familial Idiopathic Cardiomyopathy,Idiopathic Cardiomyopathies, Familial,Idiopathic Cardiomyopathy, Familial,Idiopathic Dilated Cardiomyopathies,Idiopathic Dilated Cardiomyopathy
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D003326	Coronary Circulation	The circulation of blood through the CORONARY VESSELS of the HEART.	Circulation, Coronary
D004452	Echocardiography	Ultrasonic recording of the size, motion, and composition of the heart and surrounding tissues. The standard approach is transthoracic.	Echocardiography, Contrast,Echocardiography, Cross-Sectional,Echocardiography, M-Mode,Echocardiography, Transthoracic,Echocardiography, Two-Dimensional,Transthoracic Echocardiography,2-D Echocardiography,2D Echocardiography,Contrast Echocardiography,Cross-Sectional Echocardiography,Echocardiography, 2-D,Echocardiography, 2D,M-Mode Echocardiography,Two-Dimensional Echocardiography,2 D Echocardiography,Cross Sectional Echocardiography,Echocardiography, 2 D,Echocardiography, Cross Sectional,Echocardiography, M Mode,Echocardiography, Two Dimensional,M Mode Echocardiography,Two Dimensional Echocardiography
D005260	Female		Females