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Squamous cell carcinoma arising in Verneuil's disease. 2008

Achour Jamel Ben, and Ibtissem Bouasker, and Haythem Najah, and Hazem Zribi, and Riadh Bedoui, and Fethi Guesmi, and Mohamed Aziz Hani, and Ramzi Nouira, and Ayoub Zoghlami, and Nabil Najah
Department B of Surgery. Charles Nicolle's Hospital, Tunis, Tunisia.

BACKGROUND Verneuil's disease or hidradenitis suppurativa is a chronic suppurative, and cicatricial inflammatory disease, mainly affecting apocrine-bearing area of the skin. Squamous cell carcinoma is an uncommon but a frightening complication of hidradenitis suppurativa. OBJECTIVE To report a new case of squamous cell carcinoma arising in Verneuil's disease. METHODS We reported a case of 60 year old man with a 30 years history of hidradenitis suppurativa in which squamous cell carcinoma arise. A wide surgical excision removing the tumour and leaving a large defect was performed. The patient had a well recovery, wounds healed well by primary intention. No recurrence observed at 18 months of follow up. CONCLUSIONS Squamous cell carcinoma is an uncommon complication of hidradenitis suppurativa. Surgical excision represents also the treatment of choice.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002294 Carcinoma, Squamous Cell A carcinoma derived from stratified SQUAMOUS EPITHELIAL CELLS. It may also occur in sites where glandular or columnar epithelium is normally present. (From Stedman, 25th ed) Carcinoma, Epidermoid,Carcinoma, Planocellular,Carcinoma, Squamous,Squamous Cell Carcinoma,Carcinomas, Epidermoid,Carcinomas, Planocellular,Carcinomas, Squamous,Carcinomas, Squamous Cell,Epidermoid Carcinoma,Epidermoid Carcinomas,Planocellular Carcinoma,Planocellular Carcinomas,Squamous Carcinoma,Squamous Carcinomas,Squamous Cell Carcinomas
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001005 Anus Neoplasms Tumors or cancer of the ANAL CANAL. Anal Cancer,Cancer of Anus,Anal Neoplasms,Cancer of the Anus,Neoplasms, Anal,Neoplasms, Anus,Anal Cancers,Anal Neoplasm,Anus Cancer,Anus Cancers,Anus Neoplasm,Cancer, Anal,Cancers, Anal,Neoplasm, Anal,Neoplasm, Anus
D012878 Skin Neoplasms Tumors or cancer of the SKIN. Cancer of Skin,Skin Cancer,Cancer of the Skin,Neoplasms, Skin,Cancer, Skin,Cancers, Skin,Neoplasm, Skin,Skin Cancers,Skin Neoplasm
D017497 Hidradenitis Suppurativa A chronic suppurative and cicatricial disease of the apocrine glands occurring chiefly in the axillae in women and in the groin and anal regions in men. It is characterized by poral occlusion with secondary bacterial infection, evolving into abscesses which eventually rupture. As the disease becomes chronic, ulcers appear, sinus tracts enlarge, fistulas develop, and fibrosis and scarring become evident. Acne Inversa,Hidradenitides, Suppurative,Hidradenitis, Suppurative,Suppurative Hidradenitides,Suppurative Hidradenitis,Acne Inversas,Inversa, Acne,Inversas, Acne

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