Biomaterial Database

Development of calcium silicate/calcium phosphate cement for bone regeneration. 2007

Han Guo, and Jie Wei, and Yuan Yuan, and Changsheng Liu

State Key Laboratory of Bioreactor Engineering, and Engineering Research Center for Biomedical Materials of Ministry of Education, East China University of Science and Technology, Shanghai 200237, People's Republic of China.

A new type of composite bone cement was prepared and investigated by adding calcium silicate (CS) to calcium phosphate cement (CPC). Low-crystalline CS prepared by heat treatment at low temperature had excellent bioactivity and degradability. Adding CS to CPC did not affect the phase composition and chemical structure of CPC, and had a little effect on the setting time and compressive strength of the composite cement. CS could effectively improve the in vitro and in vivo bioactivity of CPC, and enhance the cell proliferation on the CPC material. The introduction of CS is an effective way to improve the bioactivity and degradability of CPC, which will provide a new strategy to modify CPC.

UI	MeSH Term	Description	Entries
D008422	Materials Testing	The testing of materials and devices, especially those used for PROSTHESES AND IMPLANTS; SUTURES; TISSUE ADHESIVES; etc., for hardness, strength, durability, safety, efficacy, and biocompatibility.	Biocompatibility Testing,Biocompatible Materials Testing,Hemocompatibility Testing,Testing, Biocompatible Materials,Testing, Hemocompatible Materials,Hemocompatibility Testings,Hemocompatible Materials Testing,Materials Testing, Biocompatible,Materials Testing, Hemocompatible,Testing, Biocompatibility,Testing, Hemocompatibility,Testing, Materials,Testings, Biocompatibility
D001843	Bone Cements	Adhesives used to fix prosthetic devices to bones and to cement bone to bone in difficult fractures. Synthetic resins are commonly used as cements. A mixture of monocalcium phosphate, monohydrate, alpha-tricalcium phosphate, and calcium carbonate with a sodium phosphate solution is also a useful bone paste.	Bone Cement,Bone Glues,Bone Pastes,Bone Glue,Bone Paste,Cement, Bone,Cements, Bone,Glue, Bone,Glues, Bone,Paste, Bone,Pastes, Bone
D001861	Bone Regeneration	Renewal or repair of lost bone tissue. It excludes BONY CALLUS formed after BONE FRACTURES but not yet replaced by hard bone.	Osteoconduction,Bone Regenerations,Regeneration, Bone,Regenerations, Bone
D002130	Calcium Phosphates	Calcium salts of phosphoric acid. These compounds are frequently used as calcium supplements.	Phosphates, Calcium
D002460	Cell Line	Established cell cultures that have the potential to propagate indefinitely.	Cell Lines,Line, Cell,Lines, Cell
D002470	Cell Survival	The span of viability of a cell characterized by the capacity to perform certain functions such as metabolism, growth, reproduction, some form of responsiveness, and adaptability.	Cell Viability,Cell Viabilities,Survival, Cell,Viabilities, Cell,Viability, Cell
D004548	Elasticity	Resistance and recovery from distortion of shape.
D006244	Hardness	The mechanical property of material that determines its resistance to force. HARDNESS TESTS measure this property.	Hardnesses
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D017610	Calcium Compounds	Inorganic compounds that contain calcium as an integral part of the molecule.	Compounds, Calcium