Biomaterial Database

Conjoined twins in a trichorionic quadruplet pregnancy after ovulation induction with clomiphene citrate. 2008

Inanc Mendilcioglu, and Mehmet Simsek

Department of Obstetrics and Gynecology, Akdeniz University, School of Medicine, Antalya, Turkey. imendilcioglu@hotmail.com

OBJECTIVE We report a case of conjoined twins in a trichorionic quadruplet pregnancy after ovulation induction with clomiphene citrate for anovulation. METHODS The diagnosis of a trichorionic quadruplet pregnancy was made in routine ultrasound at 11 weeks' gestation. RESULTS Conjoined twinning was thoracopagus and presented with increased nuchal translucency. Selective termination of the conjoined twins was performed with potassium chloride injection. The patient delivered 2 healthy infants after an uneventful follow-up. CONCLUSIONS Monozygotic twinning has increased with widespread usage of ovulation induction agents and assisted reproductive techniques. Early detection of conjoined twinning and chorionicity is essential for an optimal obstetric management and outcome.

UI	MeSH Term	Description	Entries
D010062	Ovulation Induction	Techniques for the artifical induction of ovulation, the rupture of the follicle and release of the ovum.	Ovarian Stimulation,Ovarian Stimulations,Stimulation, Ovarian,Stimulations, Ovarian
D011247	Pregnancy	The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.	Gestation,Pregnancies
D011783	Quadruplets	Four individuals derived from four FETUSES that were fertilized at or about the same time, developed in the UTERUS simultaneously, and born to the same mother.	Quadruplet
D002996	Clomiphene	A triphenyl ethylene stilbene derivative which is an estrogen agonist or antagonist depending on the target tissue. Note that ENCLOMIPHENE and ZUCLOMIPHENE are the (E) and (Z) isomers of Clomiphene respectively.	Chloramiphene,Clomifene,Clomid,Clomide,Clomifen,Clomiphene Citrate,Clomiphene Hydrochloride,Clostilbegit,Dyneric,Gravosan,Klostilbegit,Serophene,Citrate, Clomiphene,Hydrochloride, Clomiphene
D005260	Female		Females
D005300	Fertility Agents, Female	Compounds which increase the capacity to conceive in females.	Fertility Agents, Female, Hormonal,Fertility Agents, Female, Synthetic,Infertility Agents, Female,Female Fertility Agents, Synthetic,Infertility Drugs, Female,Synthetic Female Fertility Agents,Agents, Female Fertility,Agents, Female Infertility,Drugs, Female Infertility,Female Fertility Agents,Female Infertility Agents,Female Infertility Drugs
D005315	Fetal Diseases	Pathophysiological conditions of the FETUS in the UTERUS. Some fetal diseases may be treated with FETAL THERAPIES.	Embryopathies,Disease, Fetal,Diseases, Fetal,Embryopathy,Fetal Disease
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D014428	Twins, Conjoined	MONOZYGOTIC TWINS who are joined in utero. They may be well developed and share only a superficial connection, often in the frontal, transverse or sagittal body plane, or they may share a partial duplication of a body structure. Alternatively, there may be a small and incompletely developed twin conjoined to a larger, more fully developed twin.	Siamese Twins,Twins, Siamese,Conjoined Twin,Conjoined Twins,Siamese Twin,Twin, Conjoined,Twin, Siamese