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An infectious process was reproduced in the culture of chick embryo cells by means of DNA isolated from Rous chick sarcoma tissue (Carr-Zilber strain). This DNA preparation displays biological activity also in the culture of human embryo diploid cells (HEDC) which is manifested in: 1. discontinuous synthesis of avian oncovirus group-specific antigen; 2. enhancement of proliferative activity and morphological transformation of human cells; 3. continuous presence of virus-specific sequences as revealed by DNA/RNA hybridization. Producing complete oncornavirus by means of DNA isolated from Rous chick sarcoma in HEDC was unsuccessful. DNA preparation from gs negative chick embryo cells shows no infectious activity in HEDC culture.
P G Knyazev, and
L P Korobitsyn, and
A I Zhudina, and
V I Shmelkova, and
O K Kuznetsov, and
A M Dyadkova, and
I F Seitz
January 1966,
Experimental cell research,
P G Knyazev, and
L P Korobitsyn, and
A I Zhudina, and
V I Shmelkova, and
O K Kuznetsov, and
A M Dyadkova, and
I F Seitz
September 1968,
Biochemical and biophysical research communications,
P G Knyazev, and
L P Korobitsyn, and
A I Zhudina, and
V I Shmelkova, and
O K Kuznetsov, and
A M Dyadkova, and
I F Seitz
August 1964,
Proceedings of the National Academy of Sciences of the United States of America,
P G Knyazev, and
L P Korobitsyn, and
A I Zhudina, and
V I Shmelkova, and
O K Kuznetsov, and
A M Dyadkova, and
I F Seitz
September 1969,
International journal of cancer,
P G Knyazev, and
L P Korobitsyn, and
A I Zhudina, and
V I Shmelkova, and
O K Kuznetsov, and
A M Dyadkova, and
I F Seitz
December 1959,
Virology,
P G Knyazev, and
L P Korobitsyn, and
A I Zhudina, and
V I Shmelkova, and
O K Kuznetsov, and
A M Dyadkova, and
I F Seitz
October 1962,
Cancer research,
P G Knyazev, and
L P Korobitsyn, and
A I Zhudina, and
V I Shmelkova, and
O K Kuznetsov, and
A M Dyadkova, and
I F Seitz
October 1972,
The Journal of general virology,
P G Knyazev, and
L P Korobitsyn, and
A I Zhudina, and
V I Shmelkova, and
O K Kuznetsov, and
A M Dyadkova, and
I F Seitz
March 1982,
Experimental cell research,
P G Knyazev, and
L P Korobitsyn, and
A I Zhudina, and
V I Shmelkova, and
O K Kuznetsov, and
A M Dyadkova, and
I F Seitz
January 1985,
Archives of biochemistry and biophysics,
P G Knyazev, and
L P Korobitsyn, and
A I Zhudina, and
V I Shmelkova, and
O K Kuznetsov, and
A M Dyadkova, and
I F Seitz
May 1968,
Poultry science,
