Biomaterial Database

The use of endothelial seeding of prosthetic arterial bypass grafts. 1991

M B Herring

Endothelial seeding is the transplantation of vascular lining cells. On the basis of animal studies and theoretical considerations, seeding is expected to reduce acute thrombosis and stenoses because of NFH when segments of the vascular system are denuded of endothelium. Endothelialization may reduce the susceptibility of synthetic grafts to blood-borne bacterial infection. Seeding demonstrably transfers endothelium in humans. The indications for its use are limited to clinical trials in aorta-femoral and femoral-popliteal bypass operations, and the results of those trials will begin to define its indications further. In the future, endothelium may be applied to tibial and coronary synthetic arterial grafts; sites of endarterectomy, PTA, atherectomy, and laser treatments; vascular access; and venous replacement grafts.

UI	MeSH Term	Description	Entries
D001807	Blood Vessel Prosthesis	Device constructed of either synthetic or biological material that is used for the repair of injured or diseased blood vessels.	Vascular Prosthesis,Blood Vessel Prostheses,Tissue-Engineered Vascular Graft,Graft, Tissue-Engineered Vascular,Grafts, Tissue-Engineered Vascular,Prostheses, Blood Vessel,Prostheses, Vascular,Prosthesis, Blood Vessel,Prosthesis, Vascular,Tissue Engineered Vascular Graft,Tissue-Engineered Vascular Grafts,Vascular Graft, Tissue-Engineered,Vascular Grafts, Tissue-Engineered,Vascular Prostheses,Vessel Prostheses, Blood,Vessel Prosthesis, Blood
D004730	Endothelium, Vascular	Single pavement layer of cells which line the luminal surface of the entire vascular system and regulate the transport of macromolecules and blood components.	Capillary Endothelium,Vascular Endothelium,Capillary Endotheliums,Endothelium, Capillary,Endotheliums, Capillary,Endotheliums, Vascular,Vascular Endotheliums
D006083	Graft Occlusion, Vascular	Obstruction of flow in biological or prosthetic vascular grafts.	Graft Restenosis, Vascular,Vascular Graft Occlusion,Vascular Graft Restenosis,Graft Restenoses, Vascular,Occlusion, Vascular Graft,Restenosis, Vascular Graft
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001157	Arterial Occlusive Diseases	Pathological processes which result in the partial or complete obstruction of ARTERIES. They are characterized by greatly reduced or absence of blood flow through these vessels. They are also known as arterial insufficiency.	Arterial Obstructive Diseases,Arterial Occlusion,Arterial Obstructive Disease,Arterial Occlusions,Arterial Occlusive Disease,Disease, Arterial Obstructive,Disease, Arterial Occlusive,Obstructive Disease, Arterial,Occlusion, Arterial,Occlusive Disease, Arterial
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor
D016378	Tissue Transplantation	Transference of tissue within an individual, between individuals of the same species, or between individuals of different species.	Grafting, Tissue,Transplantation, Tissue,Tissue Grafting