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[Culture of anaerobic bacteria and antibiotic sensitivity test in ocular infectious diseases]. 1991

X Liu
Department of Ophthalmology, Second Affiliated Hospital Third Military Medical University, Chongquing.

Anaerobes were isolated from 43.9% of 116 eyes with infectious diseases and 21.4% of 140 normal conjunctival sacs. The predominant anaerobes were peptococcus (28.6%) in the former and propionibacterium (53.3%) in the latter. In eyes with infection, only anaerobes were isolated from 27, and a mixture of anaerobes and aerobes in 24. The sensitivity of anaerobes (68 strains) to 10 antibiotics differed significantly from that of aerobes (102 strains). Most anaerobes are sensitive to chloramphenicol and cephaloridine, but not to aminoglycosides or polymyxin B. Therefore, when an ocular infection shows a negative aerobic culture, anaerobic infection should be suspected and chloramphenicol is indicated as first choice for treatment.

UI MeSH Term Description Entries
D008297 Male Males
D008826 Microbial Sensitivity Tests Any tests that demonstrate the relative efficacy of different chemotherapeutic agents against specific microorganisms (i.e., bacteria, fungi, viruses). Bacterial Sensitivity Tests,Drug Sensitivity Assay, Microbial,Minimum Inhibitory Concentration,Antibacterial Susceptibility Breakpoint Determination,Antibiogram,Antimicrobial Susceptibility Breakpoint Determination,Bacterial Sensitivity Test,Breakpoint Determination, Antibacterial Susceptibility,Breakpoint Determination, Antimicrobial Susceptibility,Fungal Drug Sensitivity Tests,Fungus Drug Sensitivity Tests,Sensitivity Test, Bacterial,Sensitivity Tests, Bacterial,Test, Bacterial Sensitivity,Tests, Bacterial Sensitivity,Viral Drug Sensitivity Tests,Virus Drug Sensitivity Tests,Antibiograms,Concentration, Minimum Inhibitory,Concentrations, Minimum Inhibitory,Inhibitory Concentration, Minimum,Inhibitory Concentrations, Minimum,Microbial Sensitivity Test,Minimum Inhibitory Concentrations,Sensitivity Test, Microbial,Sensitivity Tests, Microbial,Test, Microbial Sensitivity,Tests, Microbial Sensitivity
D009877 Endophthalmitis Suppurative inflammation of the tissues of the internal structures of the eye frequently associated with an infection. Ophthalmia,Infectious Endophthalmitis,Endophthalmitides,Endophthalmitides, Infectious,Endophthalmitis, Infectious,Infectious Endophthalmitides,Ophthalmias
D010460 Peptococcus A genus of gram-positive, anaerobic, coccoid bacteria that is part of the normal flora of the mouth, upper respiratory tract, and large intestine in humans. Its organisms cause infections of soft tissues and bacteremias.
D011424 Propionibacterium A genus of gram-positive, rod-shaped bacteria whose cells occur singly, in pairs or short chains, in V or Y configurations, or in clumps resembling letters of the Chinese alphabet. Its organisms are found in cheese and dairy products as well as on human skin and can occasionally cause soft tissue infections.
D002509 Cephaloridine A cephalosporin antibiotic. Cefaloridine,Cephalomycine,Cephaloridin,Ceporin
D002701 Chloramphenicol An antibiotic first isolated from cultures of Streptomyces venequelae in 1947 but now produced synthetically. It has a relatively simple structure and was the first broad-spectrum antibiotic to be discovered. It acts by interfering with bacterial protein synthesis and is mainly bacteriostatic. (From Martindale, The Extra Pharmacopoeia, 29th ed, p106) Cloranfenicol,Kloramfenikol,Levomycetin,Amphenicol,Amphenicols,Chlornitromycin,Chlorocid,Chloromycetin,Detreomycin,Ophthochlor,Syntomycin
D003234 Conjunctivitis, Bacterial Purulent infections of the conjunctiva by several species of gram-negative, gram-positive, or acid-fast organisms. Some of the more commonly found genera causing conjunctival infections are Haemophilus, Streptococcus, Neisseria, and Chlamydia. Bacterial Conjunctivitis,Conjunctivitis, Mucopurulent,Conjunctivitis, Purulent,Bacterial Conjunctivitides,Conjunctivitides, Bacterial,Conjunctivitides, Mucopurulent,Conjunctivitides, Purulent,Mucopurulent Conjunctivitides,Mucopurulent Conjunctivitis,Purulent Conjunctivitides,Purulent Conjunctivitis
D003607 Dacryocystitis Inflammation of the lacrimal sac. (Dorland, 27th ed) Dacryoadenitis,Dacryoadenitides,Dacryocystitides
D005260 Female Females

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