BIOMAT Database Logo BIOMAT Database Logo

[Famotidine--a new histamine H2 receptor blockader]. 1991

P Ia Grigor'ev, and V A Isakov, and E P Iakovenko, and S M Davydov, and Z I Vasil'eva

UI MeSH Term Description Entries
D010437 Peptic Ulcer Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS). Gastroduodenal Ulcer,Marginal Ulcer,Gastroduodenal Ulcers,Marginal Ulcers,Peptic Ulcers,Ulcer, Gastroduodenal,Ulcer, Marginal,Ulcer, Peptic,Ulcers, Gastroduodenal,Ulcers, Marginal,Ulcers, Peptic
D011970 Receptors, Histamine H2 A class of histamine receptors discriminated by their pharmacology and mode of action. Histamine H2 receptors act via G-proteins to stimulate ADENYLYL CYCLASES. Among the many responses mediated by these receptors are gastric acid secretion, smooth muscle relaxation, inotropic and chronotropic effects on heart muscle, and inhibition of lymphocyte function. (From Biochem Soc Trans 1992 Feb;20(1):122-5) Histamine H2 Receptors,H2 Receptors,Receptors, H2,H2 Receptors, Histamine
D002927 Cimetidine A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output. Altramet,Biomet,Biomet400,Cimetidine HCl,Cimetidine Hydrochloride,Eureceptor,Histodil,N-Cyano-N'-methyl-N''-(2-(((5-methyl-1H-imidazol-4-yl)methyl)thio)ethyl)guanidine,SK&F-92334,SKF-92334,Tagamet,HCl, Cimetidine,Hydrochloride, Cimetidine,SK&F 92334,SK&F92334,SKF 92334,SKF92334
D005744 Gastric Acid Hydrochloric acid present in GASTRIC JUICE. Hydrochloric Acid, Gastric,Acids, Gastric,Acids, Gastric Hydrochloric,Gastric Acids,Gastric Hydrochloric Acid,Gastric Hydrochloric Acids,Hydrochloric Acids, Gastric
D005753 Gastric Mucosa Lining of the STOMACH, consisting of an inner EPITHELIUM, a middle LAMINA PROPRIA, and an outer MUSCULARIS MUCOSAE. The surface cells produce MUCUS that protects the stomach from attack by digestive acid and enzymes. When the epithelium invaginates into the LAMINA PROPRIA at various region of the stomach (CARDIA; GASTRIC FUNDUS; and PYLORUS), different tubular gastric glands are formed. These glands consist of cells that secrete mucus, enzymes, HYDROCHLORIC ACID, or hormones. Cardiac Glands,Gastric Glands,Pyloric Glands,Cardiac Gland,Gastric Gland,Gastric Mucosas,Gland, Cardiac,Gland, Gastric,Gland, Pyloric,Glands, Cardiac,Glands, Gastric,Glands, Pyloric,Mucosa, Gastric,Mucosas, Gastric,Pyloric Gland
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D015738 Famotidine A competitive histamine H2-receptor antagonist. Its main pharmacodynamic effect is the inhibition of gastric secretion. Famotidine Hydrochloride,MK-208,Pepcid,YM-11170,MK 208,MK208,YM 11170,YM11170

Related Publications

P Ia Grigor'ev, and V A Isakov, and E P Iakovenko, and S M Davydov, and Z I Vasil'eva
[Ranitidine: a new histamine H2 receptor blockader].
May 1986, Zhonghua nei ke za zhi,
P Ia Grigor'ev, and V A Isakov, and E P Iakovenko, and S M Davydov, and Z I Vasil'eva
[Famotidine--a new histamine H2 antagonist].
October 1990, Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke,
P Ia Grigor'ev, and V A Isakov, and E P Iakovenko, and S M Davydov, and Z I Vasil'eva
Effects of famotidine, a new histamine H2-receptor antagonist, on renal function.
June 1989, Nihon Jinzo Gakkai shi,
P Ia Grigor'ev, and V A Isakov, and E P Iakovenko, and S M Davydov, and Z I Vasil'eva
[Famotidine. Pharmacologic and clinical profile of the new histamine H2 receptor antagonist].
April 1986, Fortschritte der Medizin,
P Ia Grigor'ev, and V A Isakov, and E P Iakovenko, and S M Davydov, and Z I Vasil'eva
New histamine H2-receptor antagonists.
June 1980, Hepato-gastroenterology,
P Ia Grigor'ev, and V A Isakov, and E P Iakovenko, and S M Davydov, and Z I Vasil'eva
Famotidine: clinical applications of a new H2-receptor antagonist. Introduction.
October 1986, The American journal of medicine,
P Ia Grigor'ev, and V A Isakov, and E P Iakovenko, and S M Davydov, and Z I Vasil'eva
Effect of a histamine H2-receptor antagonist, famotidine, on gastric secretion in healthy subjects.
January 1987, Clinical therapeutics,
P Ia Grigor'ev, and V A Isakov, and E P Iakovenko, and S M Davydov, and Z I Vasil'eva
[Effect of a new H2 receptor antagonist, famotidine, on gastric secretion].
September 1986, Bollettino della Societa italiana di biologia sperimentale,
P Ia Grigor'ev, and V A Isakov, and E P Iakovenko, and S M Davydov, and Z I Vasil'eva
Famotidine in the treatment of duodenal ulcers resistant to other histamine H2-receptor antagonists.
January 1989, The Journal of international medical research,
P Ia Grigor'ev, and V A Isakov, and E P Iakovenko, and S M Davydov, and Z I Vasil'eva
Interaction of famotidine, an H2 histamine receptor antagonist, with conventional antiepileptic drugs in mice.
June 2014, Pharmacological reports : PR,
Copied contents to your clipboard!