BIOMAT Database Logo BIOMAT Database Logo

Cyanopeptoline CB071: a cyclic depsipeptide isolated from the freshwater cyanobacterium Aphanocapsa sp. 2008

Hyukjae Choi, and Sun Kwan Oh, and Wonho Yih, and Jungwook Chin, and Heonjoong Kang, and Jung-Rae Rho
Center for Marine Natural Products and Drug Discovery, School of Earth and Environmental Sciences, Seoul National University, Seoul, Korea.

Cyanopeptolin CB071 (1), a trypsin inhibitor, was isolated from the freshwater cyanobacterium Aphanocapsa sp. Its complete structure was determined by detailed NMR spectroscopy and MS analyses, along with chemical reactions. The compound showed inhibition of trypsin at a concentration of IC50=2.5 microM.

UI MeSH Term Description Entries
D005618 Fresh Water Water containing no significant amounts of salts, such as water from RIVERS and LAKES. Freshwater,Fresh Waters,Freshwaters,Water, Fresh,Waters, Fresh
D000458 Cyanobacteria A phylum of oxygenic photosynthetic bacteria comprised of unicellular to multicellular bacteria possessing CHLOROPHYLL a and carrying out oxygenic PHOTOSYNTHESIS. Cyanobacteria are the only known organisms capable of fixing both CARBON DIOXIDE (in the presence of light) and NITROGEN. Cell morphology can include nitrogen-fixing heterocysts and/or resting cells called akinetes. Formerly called blue-green algae, cyanobacteria were traditionally treated as ALGAE. Algae, Blue-Green,Blue-Green Bacteria,Cyanophyceae,Algae, Blue Green,Bacteria, Blue Green,Bacteria, Blue-Green,Blue Green Algae,Blue Green Bacteria,Blue-Green Algae
D014361 Trypsin Inhibitors Serine proteinase inhibitors which inhibit trypsin. They may be endogenous or exogenous compounds. Trypsin Inhibitor,Inhibitor, Trypsin,Inhibitors, Trypsin
D015394 Molecular Structure The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds. Structure, Molecular,Molecular Structures,Structures, Molecular
D047630 Depsipeptides Compounds consisting of chains of AMINO ACIDS alternating with CARBOXYLIC ACIDS via ester and amide linkages. They are commonly cyclized. Cyclic Depsipeptide,Cyclodepsipeptide,Depsipeptide,Peptolide,Peptolides,Cryptophycins,Cyclodepsipeptides,Depsipeptides, Cyclic,Cyclic Depsipeptides,Depsipeptide, Cyclic

Related Publications

Hyukjae Choi, and Sun Kwan Oh, and Wonho Yih, and Jungwook Chin, and Heonjoong Kang, and Jung-Rae Rho
Ulongapeptin, a cytotoxic cyclic depsipeptide from a Palauan marine cyanobacterium Lyngbya sp.
May 2003, Journal of natural products,
Hyukjae Choi, and Sun Kwan Oh, and Wonho Yih, and Jungwook Chin, and Heonjoong Kang, and Jung-Rae Rho
Coibamide A, a potent antiproliferative cyclic depsipeptide from the Panamanian marine cyanobacterium Leptolyngbya sp.
May 2008, Journal of the American Chemical Society,
Hyukjae Choi, and Sun Kwan Oh, and Wonho Yih, and Jungwook Chin, and Heonjoong Kang, and Jung-Rae Rho
Benderamide A, a Cyclic Depsipeptide from a Singapore Collection of Marine Cyanobacterium cf. Lyngbya sp.
October 2018, Marine drugs,
Hyukjae Choi, and Sun Kwan Oh, and Wonho Yih, and Jungwook Chin, and Heonjoong Kang, and Jung-Rae Rho
Stigonemapeptin, an Ahp-containing depsipeptide with elastase inhibitory activity from the bloom-forming freshwater cyanobacterium Stigonema sp.
April 2012, Journal of natural products,
Hyukjae Choi, and Sun Kwan Oh, and Wonho Yih, and Jungwook Chin, and Heonjoong Kang, and Jung-Rae Rho
Lyngbyastatins 8-10, elastase inhibitors with cyclic depsipeptide scaffolds isolated from the marine cyanobacterium Lyngbya semiplena.
November 2009, Marine drugs,
Hyukjae Choi, and Sun Kwan Oh, and Wonho Yih, and Jungwook Chin, and Heonjoong Kang, and Jung-Rae Rho
Minutissamides E-L, antiproliferative cyclic lipodecapeptides from the cultured freshwater cyanobacterium cf. Anabaena sp.
October 2012, Bioorganic & medicinal chemistry,
Hyukjae Choi, and Sun Kwan Oh, and Wonho Yih, and Jungwook Chin, and Heonjoong Kang, and Jung-Rae Rho
Isolation and Total Synthesis of Kinenzoline, an Antitrypanosomal Linear Depsipeptide Isolated from a Marine Salileptolyngbya sp. Cyanobacterium.
September 2021, The Journal of organic chemistry,
Hyukjae Choi, and Sun Kwan Oh, and Wonho Yih, and Jungwook Chin, and Heonjoong Kang, and Jung-Rae Rho
Antifungal cyclic depsipeptide, eujavanicin A, isolated from Eupenicillium javanicum.
September 2008, Journal of natural products,
Hyukjae Choi, and Sun Kwan Oh, and Wonho Yih, and Jungwook Chin, and Heonjoong Kang, and Jung-Rae Rho
Total synthesis of odoamide, a novel cyclic depsipeptide, from an Okinawan marine cyanobacterium.
September 2016, Organic & biomolecular chemistry,
Hyukjae Choi, and Sun Kwan Oh, and Wonho Yih, and Jungwook Chin, and Heonjoong Kang, and Jung-Rae Rho
Thioic O-acid ester in sulfolipid isolated from freshwater picoplankton cyanobacterium, Synechococcus sp.
July 1993, Biochimica et biophysica acta,
Copied contents to your clipboard!