Biomaterial Database

[Epidermolysis bullosa and dermo-epidermic junction. Clinico-pathologic correlation]. 1991

F G Rodrigo, and A J Mayer-da-Silva

Hospital de Santa Maria, Clínica Dermatológica Universitária de Lisboa.

Epidermolysis bullosa encompasses a group of hereditary diseases clinically and pathologically characteristic. In this review the grouping criteria commonly accepted for their classification are described. The cleavage phenomena observed in these diseases are analysed in accordance with the concept of a skin area including dermal and epidermal interrelated structures--the dermo-epidermal junction zone. Finally in the most expressive forms the clinical manifestations, diagnosis and treatment are reviewed.

UI	MeSH Term	Description	Entries
D004817	Epidermis	The external, nonvascular layer of the skin. It is made up, from within outward, of five layers of EPITHELIUM: (1) basal layer (stratum basale epidermidis); (2) spinous layer (stratum spinosum epidermidis); (3) granular layer (stratum granulosum epidermidis); (4) clear layer (stratum lucidum epidermidis); and (5) horny layer (stratum corneum epidermidis).
D004820	Epidermolysis Bullosa	Group of genetically determined disorders characterized by the blistering of skin and mucosae. There are four major forms: acquired, simple, junctional, and dystrophic. Each of the latter three has several varieties.	Acantholysis Bullosa
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man