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Hürthle tumors of the thyroid gland are uncommon lesions, histologically related to the well differentiated types of thyroid malignancies. Lesions predominantly composed of Hürthle cells are difficult for pathologists to be diagnosed and, consequently, for surgeons to be properly treated. In this report a case of Hürthle cell carcinoma was firstly treated with hemithyroidectomy plus isthmectomy; once frozen section examination revealed signs of malignancy a total thyroidectomy was performed.
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