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Cutaneous polyarteritis nodosa in a patient with Crohn's disease. 2008
Atsushi Komatsuda, and
Koji Kinoshita, and
Masaru Togashi, and
Nobuki Maki, and
Rie Masai, and
Hidetaka Niitsu, and
Setsuya Ohtani, and
Masato Sageshima, and
Ken-ichi Sawada, and
Hideki Wakui
Third Department of Internal Medicine, Akita University School of Medicine, and Department of Hematology, Municipal Akita General Hospital, 1-1-1 Hondo, Akita, 010-8543, Japan. komatsud@med.akita-u.ac.jp
A 19-year-old Japanese woman with a 4-year history of Crohn's disease (CD) developed high fever, polyarthralgia, and painful subcutaneous nodules of the legs. A skin biopsy showed panarteritis with fibrinoid necrosis in the deep dermis. Endoscopic examination showed aphthous lesions in the entire colon. She was diagnosed with cutaneous polyarteritis nodosa (PAN) associated with CD. Steroid therapy improved her symptoms. To our knowledge, this is the first Japanese case of cutaneous PAN associated with CD.
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