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Between April 1982 and December 1988, we performed 611 fine needle aspiration (FNA) biopsies in 502 patients with solitary thyroid nodules. The biopsy results were classified as follows: unsatisfactory, 19%; benign, 53%; suspicious, 23%; and malignant, 5%. Malignant lesions were found at surgery in 24 of 25 patients with malignant cytology and 31 of 68 patients with suspicious cytology. Autonomous nodules, obviating the need for surgery, were detected in 5 of 36 (14%) patients with cytology suspicious for follicular neoplasm. We conclude that FNA biopsy of the thyroid nodule is a safe and accurate diagnostic test. Thyroid scintigraphy remains useful in patients with cytologic results suspicious for follicular neoplasm. A cost-effective strategy for managing thyroid nodules is presented.
R H Caplan, and
P J Strutt, and
W A Kisken, and
S M Wester
September 1982,
Texas medicine,
R H Caplan, and
P J Strutt, and
W A Kisken, and
S M Wester
January 1995,
Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists,
R H Caplan, and
P J Strutt, and
W A Kisken, and
S M Wester
October 2001,
Archives of disease in childhood,
R H Caplan, and
P J Strutt, and
W A Kisken, and
S M Wester
July 1983,
Annals of surgery,
R H Caplan, and
P J Strutt, and
W A Kisken, and
S M Wester
August 1988,
Indiana medicine : the journal of the Indiana State Medical Association,
R H Caplan, and
P J Strutt, and
W A Kisken, and
S M Wester
October 1988,
Cancer,
R H Caplan, and
P J Strutt, and
W A Kisken, and
S M Wester
January 1994,
Cleveland Clinic journal of medicine,
R H Caplan, and
P J Strutt, and
W A Kisken, and
S M Wester
March 2002,
Acta radiologica (Stockholm, Sweden : 1987),
R H Caplan, and
P J Strutt, and
W A Kisken, and
S M Wester
November 1984,
Zhonghua wai ke za zhi [Chinese journal of surgery],
R H Caplan, and
P J Strutt, and
W A Kisken, and
S M Wester
March 2021,
Head & neck,
