-transparent.png){kind=logo}
OBJECTIVE The present study was designed to determine the prevalence of factor V Leiden (FVL), prothrombin gene G20210A (PTG) and methylenetetrahydrofolate reductase (MTHFR C677T) mutations in women from South-Western Greece with recurrent fetal loss (RFL) and negative personal thromboembolic history. METHODS 212 women with RFL and 181 women with at least two pregnancies with normal outcome and no history of pregnancy loss were investigated for the commonest thrombophilic mutations (FVL, PTG, MTHFR C677T). Comparisons between groups were performed by Pearson's chi-square test and odd ratios were calculated. RESULTS An abnormal genotype was detected in 49 women of the study group (23.1%) and in 41 women of the control group (22.6%). CONCLUSIONS Inherited thrombophilia screening is not indicated as an initial approach in Greek women with RFL and negative personal thromboembolic history.
A Mougiou, and
G Androutsopoulos, and
M Karakantza, and
E Theodori, and
G Decavalas, and
N Zoumbos
November 2007,
Thrombosis and haemostasis,
A Mougiou, and
G Androutsopoulos, and
M Karakantza, and
E Theodori, and
G Decavalas, and
N Zoumbos
January 2011,
Clinical and experimental obstetrics & gynecology,
A Mougiou, and
G Androutsopoulos, and
M Karakantza, and
E Theodori, and
G Decavalas, and
N Zoumbos
January 2011,
Obstetrics and gynecology international,
A Mougiou, and
G Androutsopoulos, and
M Karakantza, and
E Theodori, and
G Decavalas, and
N Zoumbos
September 2000,
Current opinion in hematology,
A Mougiou, and
G Androutsopoulos, and
M Karakantza, and
E Theodori, and
G Decavalas, and
N Zoumbos
January 2007,
Akusherstvo i ginekologiia,
A Mougiou, and
G Androutsopoulos, and
M Karakantza, and
E Theodori, and
G Decavalas, and
N Zoumbos
August 2012,
Ginekologia polska,
A Mougiou, and
G Androutsopoulos, and
M Karakantza, and
E Theodori, and
G Decavalas, and
N Zoumbos
December 2013,
Iranian Red Crescent medical journal,
A Mougiou, and
G Androutsopoulos, and
M Karakantza, and
E Theodori, and
G Decavalas, and
N Zoumbos
January 2014,
Clinical and experimental obstetrics & gynecology,
A Mougiou, and
G Androutsopoulos, and
M Karakantza, and
E Theodori, and
G Decavalas, and
N Zoumbos
October 2015,
Blood cells, molecules & diseases,
A Mougiou, and
G Androutsopoulos, and
M Karakantza, and
E Theodori, and
G Decavalas, and
N Zoumbos
September 2008,
Ginekologia polska,
