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Synthesis and antiviral evaluation of 7-fluoro-7-deaza-2-aminopurine nucleoside derivatives. 2008
Frederic Leroy, and
Dominique Chaves, and
David Dukhan, and
Richard Storer, and
Jean-Pierre Sommadossi, and
Anna Giulia Loi, and
Alessandra Cadeddu, and
Maura Fanti, and
Nadia Boscu, and
Fabiola Bassetti, and
Michel Liuzzi, and
Gilles Gosselin
Idenix Pharmaceuticals, Medicinal Chemistry Laboratory, Cap Gamma, 1682 Rue de la Valsière, 34189 Montpellier Cedex 4, France. Leroy.frederic@idenix.com
Three 7-fluoro-7-deaza-2-aminopurine nucleoside derivatives were synthesized and evaluated as potential inhibitors of RNA virus replication, including hepatitis C virus (HCV).
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