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[A case of advanced small cell lung cancer complicated by chronic renal failure treated with amrubicin]. 2008
Sumito Isogai, and
Yoshitaka Totani, and
Yasuo Kohashi, and
Yuuki Mieno, and
Hiromi Imizu, and
Yukiko Yoneda, and
Hideyasu Shimizu, and
Tami Hoshino, and
Yasuhiro Uchiyama, and
Yasuo Takeuchi, and
Masamichi Hayashi, and
Yuji Saitoh, and
Fumihiko Sasaki, and
Mitsushi Okazawa, and
Hiroki Sakakibara
Dept. Internal Medicine, Division of Respirology Medicine and Clinical Allergy, School of Medicine, Fujita Health University.
A 64-year old man first visited our clinic approximately 10 years ago because of diabetic nephropathy that had developed into chronic renal failure. He was hospitalized to examine a left S10 tumor shadow. Based on the results of these examinations, a primary left S10 T2N0M1, ED small cell lung cancer, was diagnosed. During his outpatient visits nephropathy was found. Following admission, he began dialysis (HD). During the detailed examinations, chemotherapy with amrubicin (AMR)was performed and the blood concentration of the drug was measured. The results showed no significant variations in blood concentration before and after the dialysis. While PR was achieved in this patient, a reduction in grade 4 eosinophils was observed as an adverse reaction.
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