BACKGROUND Liposarcomas of the retroperitoneal area (LSRP) are rare mesenchymal tumour, which are literary ranked among the retroperitoneal soft-tissue sarcomas, they can reach enormous size, while patients complains aren't distinctive. The most common symptoms are abdominal discomfort and distention of abdominal volume with a palpable resistention. The only successful treatment of this tumor is surgical exstirpation. CASE REPORT 1: 77-year-old patient was investigated because of gradually accruing size of the abdomen. There was a lipoid tumour in the peritoneal cavity shown by computed tomography, suspected coming out of the retroperitoneal area. During the operation we found out giant well-differentiated liposarcoma which grew from the retroperitoneal area. Postoperative period was complicated by bleeding and consequently by MOF. 14th postoperative day patient died. Dissection finding was another location of liposarcomas in the retroperitoneal area. CASE REPORT 2: 66-year-old patient was investigated because of increasing girth. Abdominal ultrasonography and CT displayed adipoid formation which filled up most of the peritoneal cavity with compression of surrounding organs. The tumour was completely resected during operation. The patient has been followed in dispensatory for two years without any signs of recurrence of the illness. CONCLUSIONS Liposarcomas are the most frequent histological type among primary retroperitoneal sarcomas. Metastatic potential of LSRP is low but these tumors often recur locally. In diagnostics and in follow-up are essential CT and MRI. Successful therapy is radical resection. It could be difficult to distinguish giant well-differentiated liposarcomas from normal retroperitoneal fat. Incomplete resection is a palliation operation without chance for long survival.