Spinal instrumentation for the correction of spinal deformity began with Harrington and his rod system. The use of the Harrington rods was limited, however, because of the need for long-segment instrumentation, distraction, and the potential for hood dislodgment and construct failure. Luque subsequently introduced the next generation of spinal fixation techniques via the concept of segmental instrumentation; his use of sublaminar wires allowed the construct to be fixated to the spine at every level. This arrangement allowed greater control over correction of spinal deformities and significantly lessened the incidence of hardware dislodgment. Modern instrumentation systems, including the use of pedicle screws, permit even greater control of the spine in multiple planes during deformity correction. Newer strategies have decreased the incidence of neurological injury during implant application and provide greater stability. A review of segmental fixation, including surgical techniques, is provided in this article.