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In the irradiated dog at different doses 250-400 R., a level plasma AMPc rise has been shown since the fourth hour with a maximum at 24 hours, returning to normal values about the thirtieth day. In irradiated at 250-300 R and secondarily enterectomised animals, nucleotide level rises 24 hours later, however this phenomenon is less intensive and later irradiated at 350 and 400 R.
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