BIOMAT Database Logo BIOMAT Database Logo

Incidence and prognostic value of right ventricular failure in acute respiratory distress syndrome. 2009

David Osman, and Xavier Monnet, and Vincent Castelain, and Nadia Anguel, and Josiane Warszawski, and Jean-Louis Teboul, and Christian Richard, and
Service de Réanimation Médicale, Hôpital de Bicêtre, Centre Hospitalo-Universitaire de Bicêtre, Assistance Publique-Hôpitaux de Paris, Université Paris-11 Sud, Le Kremlin-Bicêtre, France.

OBJECTIVE To analyse the incidence and the impact on outcome of right ventricular failure (RVF) in patients with acute respiratory distress syndrome (ARDS). METHODS A total of 145 ARDS patients included in the previously published French Pulmonary Artery Catheter (PAC) study were randomly assigned to receive a PAC. All patients were ventilated according to a strategy aimed at limiting plateau pressure. The RVF was defined by the concomitant presence of: (1) a mean pulmonary artery pressure (MPAP) > 25 mmHg, (2) a central venous pressure (CVP) higher than pulmonary artery occlusion pressure (PAOP) and (3) a stroke volume index < 30 mL m(-2). RESULTS Right ventricular failure was present in 9.6% of patients. Mortality was 68% at day-90 with no difference between patients with RVF (RVF+) and without RVF (71 vs. 67%, respectively). SAPS II, PaO(2)/FiO(2) and PaCO(2) were similar in both groups. Tidal volume and I/E ratio were significantly higher in RVF+ (9.7 +/- 2.8 vs. 8.6 +/- 1.8 ml m(-2) and 0.7 +/- 0.5 vs. 0.5 +/- 0.2). Plateau pressure tended to be higher in RVF+ (28 +/- 6 vs. 25 +/- 6 cmH(2)O, NS). In multivariate analysis, PaO(2)/FiO(2), mean arterial pressure, arterial pH, SvO(2), MPAP and presence of CVP > PAOP, but not RVF, were independently associated with day-90 mortality. CONCLUSIONS In this group of patients investigated early in the course of ARDS and ventilated according to a strategy aimed at limiting plateau pressure, the presence of RVF was about 10%. Unlike MPAP and the presence of CVP > PAOP, RVF at this early stage did not appear as an independent factor of mortality.

UI MeSH Term Description Entries
D007362 Intensive Care Units Hospital units providing continuous surveillance and care to acutely ill patients. ICU Intensive Care Units,Intensive Care Unit,Unit, Intensive Care
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011379 Prognosis A prediction of the probable outcome of a disease based on a individual's condition and the usual course of the disease as seen in similar situations. Prognostic Factor,Prognostic Factors,Factor, Prognostic,Factors, Prognostic,Prognoses
D011660 Pulmonary Heart Disease Hypertrophy and dilation of the RIGHT VENTRICLE of the heart that is caused by PULMONARY HYPERTENSION. This condition is often associated with pulmonary parenchymal or vascular diseases, such as CHRONIC OBSTRUCTIVE PULMONARY DISEASE and PULMONARY EMBOLISM. Cor Pulmonale,Disease, Pulmonary Heart,Diseases, Pulmonary Heart,Heart Disease, Pulmonary,Heart Diseases, Pulmonary,Pulmonary Heart Diseases
D012128 Respiratory Distress Syndrome A syndrome characterized by progressive life-threatening RESPIRATORY INSUFFICIENCY in the absence of known LUNG DISEASES, usually following a systemic insult such as surgery or major TRAUMA. ARDS, Human,Acute Respiratory Distress Syndrome,Adult Respiratory Distress Syndrome,Pediatric Respiratory Distress Syndrome,Respiratory Distress Syndrome, Acute,Respiratory Distress Syndrome, Adult,Respiratory Distress Syndrome, Pediatric,Shock Lung,Distress Syndrome, Respiratory,Distress Syndromes, Respiratory,Human ARDS,Lung, Shock,Respiratory Distress Syndromes,Syndrome, Respiratory Distress
D012129 Respiratory Function Tests Measurement of the various processes involved in the act of respiration: inspiration, expiration, oxygen and carbon dioxide exchange, lung volume and compliance, etc. Lung Function Tests,Pulmonary Function Tests,Function Test, Pulmonary,Function Tests, Pulmonary,Pulmonary Function Test,Test, Pulmonary Function,Tests, Pulmonary Function,Function Test, Lung,Function Test, Respiratory,Function Tests, Lung,Function Tests, Respiratory,Lung Function Test,Respiratory Function Test,Test, Lung Function,Test, Respiratory Function,Tests, Lung Function,Tests, Respiratory Function
D002496 Central Venous Pressure The blood pressure in the central large VEINS of the body. It is distinguished from peripheral venous pressure which occurs in an extremity. Venous Pressure, Central,Central Venous Pressures,Pressure, Central Venous,Pressures, Central Venous,Venous Pressures, Central
D005260 Female Females
D005602 France A country in western Europe bordered by the Atlantic Ocean, the English Channel, the Mediterranean Sea, and the countries of Belgium, Germany, Italy, Spain, Switzerland, the principalities of Andorra and Monaco, and by the duchy of Luxembourg. Its capital is Paris. Corsica,Saint Pierre and Miquelon,Miquelon and Saint Pierre,Miquelon and St. Pierre,St. Pierre and Miquelon

Related Publications

David Osman, and Xavier Monnet, and Vincent Castelain, and Nadia Anguel, and Josiane Warszawski, and Jean-Louis Teboul, and Christian Richard, and
Right ventricular failure in acute respiratory distress syndrome.
September 2000, The Netherlands journal of medicine,
David Osman, and Xavier Monnet, and Vincent Castelain, and Nadia Anguel, and Josiane Warszawski, and Jean-Louis Teboul, and Christian Richard, and
Right ventricular failure in acute lung injury and acute respiratory distress syndrome.
August 2012, Minerva anestesiologica,
David Osman, and Xavier Monnet, and Vincent Castelain, and Nadia Anguel, and Josiane Warszawski, and Jean-Louis Teboul, and Christian Richard, and
Acute pulmonary hypertension and right ventricular failure in adult respiratory distress syndrome.
June 1996, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,
David Osman, and Xavier Monnet, and Vincent Castelain, and Nadia Anguel, and Josiane Warszawski, and Jean-Louis Teboul, and Christian Richard, and
Defining Right Ventricular Dysfunction in Acute Respiratory Distress Syndrome.
February 2022, Journal of cardiothoracic and vascular anesthesia,
David Osman, and Xavier Monnet, and Vincent Castelain, and Nadia Anguel, and Josiane Warszawski, and Jean-Louis Teboul, and Christian Richard, and
[Acute respiratory distress syndrome, mechanical ventilation and right ventricular function].
March 2012, Medicina intensiva,
David Osman, and Xavier Monnet, and Vincent Castelain, and Nadia Anguel, and Josiane Warszawski, and Jean-Louis Teboul, and Christian Richard, and
Acute respiratory distress syndrome, mechanical ventilation, and right ventricular function.
February 2011, Current opinion in critical care,
David Osman, and Xavier Monnet, and Vincent Castelain, and Nadia Anguel, and Josiane Warszawski, and Jean-Louis Teboul, and Christian Richard, and
Etiopathogenetic Particularities and Prognostic Impact of Right Ventricular Involvement in COVID-19-Related Acute Respiratory Distress Syndrome.
April 2022, Critical care medicine,
David Osman, and Xavier Monnet, and Vincent Castelain, and Nadia Anguel, and Josiane Warszawski, and Jean-Louis Teboul, and Christian Richard, and
Use of Right Ventricular Assisted Device for Right Heart Failure in a Patient With Acute Respiratory Distress Syndrome.
September 2021, Cureus,
David Osman, and Xavier Monnet, and Vincent Castelain, and Nadia Anguel, and Josiane Warszawski, and Jean-Louis Teboul, and Christian Richard, and
[The prognostic value of eicosanoids in the acute respiratory distress syndrome].
January 1999, Medicina clinica,
David Osman, and Xavier Monnet, and Vincent Castelain, and Nadia Anguel, and Josiane Warszawski, and Jean-Louis Teboul, and Christian Richard, and
Incidence of Acute Respiratory Distress Syndrome.
July 2016, JAMA,
Copied contents to your clipboard!