Surgical versus conservative management for odontoid fractures. 2008

Emma Shears, and Christopher P Armitstead
Spinal Unit, Royal Orthopaedic Hospital, Bristol Road, Northfield, Birmingham, West Midlands, UK, B31 2AP. shears@doctors.org.uk

BACKGROUND Fractures of the odontoid process of the second cervical vertebra can result in instability, neurological damage and death. Treatment includes conservative management (external immobilisation devices) or surgical treatment (internal fixation by posterior fusion or anterior screw fixation). OBJECTIVE To compare surgical with conservative treatment for fractures of the odontoid process. METHODS We searched the Cochrane Bone, Joint and Muscle Trauma Group Specialised Register (February 2008), the Cochrane Central Register of Controlled Trials (The Cochrane Library 2008, Issue 1), MEDLINE (1966 to February 2008), EMBASE (1988 to February 2008), LILACS (accessed February 2008), reference lists of articles and registries of ongoing trials. METHODS Randomised and quasi-randomised controlled trials comparing surgical versus conservative management of odontoid fractures. METHODS Two review authors independently examined the search results to identify trials for inclusion. RESULTS We did not identify any studies that met our inclusion criteria. We excluded one ongoing and registered study that is comparing surgery versus conservative treatment because it does not involve randomisation of treatment allocation. CONCLUSIONS There is no evidence available from adequately controlled trials to inform the decision on whether the surgical treatment of odontoid fractures gives a better outcome. A sufficiently powered good quality multicentre randomised controlled trial comparing surgery versus conservative treatment is warranted.

UI MeSH Term Description Entries
D009809 Odontoid Process The toothlike process on the upper surface of the axis, which articulates with the CERVICAL ATLAS above. Dens Axis,Axis, Dens,Odontoid Processes,Process, Odontoid,Processes, Odontoid
D005592 Fracture Fixation The use of metallic devices inserted into or through bone to hold a fracture in a set position and alignment while it heals. Skeletal Fixation,Fracture Reduction,Fixation, Fracture,Fixation, Skeletal,Fixations, Fracture,Fixations, Skeletal,Fracture Fixations,Fracture Reductions,Reduction, Fracture,Reductions, Fracture,Skeletal Fixations
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D016103 Spinal Fractures Broken bones in the vertebral column. Hangman Fracture,Hangman's Fracture,Fracture, Hangman,Fracture, Hangman's,Fracture, Spinal,Fractures, Spinal,Hangmans Fracture,Spinal Fracture

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