[Association of pregnancy-induced hypertension with small-for-gestational-age babies]. 2008

Zhen Zhang, and Ai-Guo Ren, and Rong-Wei Ye, and Jun-Chi Zheng, and Song Li, and Rui-Lan Yang, and Fei-Ran Zhang, and Tan Zhang, and Jing-Bo Zhang, and Zhu Li
Institute of Reproductive and Child Health, Peking University Health Science Center, Beijing 100083, China.

OBJECTIVE To examine the association between pregnancy-induced hypertension (PIH) and small-for-gestational-age babies (SGA) in a Chinese population. METHODS Subjects were women who delivered a singleton baby (gestational weeks: equal to or greater than 28, and less than 42) in four cities or counties in Jiangsu and Zhejiang provinces, China, during the period of 1995 - 2000. A total number of 93 743 women were included. Incidence of SGA was calculated and compared between women with or without PIH and between groups with different severities of PIH. Multiple logistic regression was used to address the relationship between PIH and SGA while controlling for maternal age, occupation, education, parity, BMI, anemia, premature rupture of membranes and fetal sex. The association between PIH and SGA was also examined according to preterm or term delivery. RESULTS The incidence of SGA in women with PIH (6.0%) was higher than women without (4.5%), and the incidence increased with severities of PIH. The adjusted relative risk rates (95% CI) of SGA in women with mild,moderate and severe PIH were 1.17 (1.01-1.34), 1.69 (1.33-2.14), and 3.50 (2.57-4.77), respectively, when confounders were controlled for. The risk ratios of SGA in women with PIH among women who delivered a preterm baby were higher than those among women who delivered a term baby. CONCLUSIONS There seemed a statistical association between PIH and SGA and women with PIH having higher incidence of SGA than those without PIH.

UI MeSH Term Description Entries
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D007236 Infant, Small for Gestational Age An infant having a birth weight lower than expected for its gestational age.
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012307 Risk Factors An aspect of personal behavior or lifestyle, environmental exposure, inborn or inherited characteristic, which, based on epidemiological evidence, is known to be associated with a health-related condition considered important to prevent. Health Correlates,Risk Factor Scores,Risk Scores,Social Risk Factors,Population at Risk,Populations at Risk,Correlates, Health,Factor, Risk,Factor, Social Risk,Factors, Social Risk,Risk Factor,Risk Factor Score,Risk Factor, Social,Risk Factors, Social,Risk Score,Score, Risk,Score, Risk Factor,Social Risk Factor
D046110 Hypertension, Pregnancy-Induced A condition in pregnant women with elevated systolic (>140 mm Hg) and diastolic (>90 mm Hg) blood pressure on at least two occasions 6 h apart. HYPERTENSION complicates 8-10% of all pregnancies, generally after 20 weeks of gestation. Gestational hypertension can be divided into several broad categories according to the complexity and associated symptoms, such as EDEMA; PROTEINURIA; SEIZURES; abnormalities in BLOOD COAGULATION and liver functions. Gestational Hypertension,Pregnancy Induced Hypertension,Transient Hypertension, Pregnancy,Hypertension, Gestational,Hypertension, Pregnancy Induced,Hypertension, Pregnancy Transient,Hypertensions, Pregnancy Induced,Induced Hypertension, Pregnancy,Induced Hypertensions, Pregnancy,Pregnancy Transient Hypertension,Pregnancy-Induced Hypertension
D055815 Young Adult A person between 19 and 24 years of age. Adult, Young,Adults, Young,Young Adults

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