Biomaterial Database

Study of the long chain bases of sphingomyelin of Entomophthora coronata. 1976

C De Bievre, and F Mariat

Sphingomyelin was isolated from a strain of Entomophthora coronata, a fungus pathogenic for humans. After hydrolysis, the long chain bases were converted to their dinitrophenyl (N2pH) derivatives and the aldehydes prepared by oxidizing these compounds with periodic acid. The aldehydes were studied by gas chromatography. Twelve different aldehydes were identified, the chain distributiion ranging from C14 to C17. The prominent chains were unsaturated. Straight and branched chains were found. The most abundant parent base which formed 52% of the total aldehyde was a 1,3-dihydroxy-2-aminohexadecene.

UI	MeSH Term	Description	Entries
D010084	Oxidation-Reduction	A chemical reaction in which an electron is transferred from one molecule to another. The electron-donating molecule is the reducing agent or reductant; the electron-accepting molecule is the oxidizing agent or oxidant. Reducing and oxidizing agents function as conjugate reductant-oxidant pairs or redox pairs (Lehninger, Principles of Biochemistry, 1982, p471).	Redox,Oxidation Reduction
D010504	Periodic Acid	A strong oxidizing agent.	Paraperiodic Acid,Periodic Acid (HIO4),Periodic Acids,Acid, Paraperiodic,Acid, Periodic,Acids, Periodic
D004773	Entomophthora	A genus of fungi in the family Entomophthoraceae, order Entomorphthorales. They are primarily parasites of insects and spiders, but have been found to cause mycotic infections of the nose in man and horses.	Entomophthoras
D005658	Fungi	A kingdom of eukaryotic, heterotrophic organisms that live parasitically as saprobes, including MUSHROOMS; YEASTS; smuts, molds, etc. They reproduce either sexually or asexually, and have life cycles that range from simple to complex. Filamentous fungi, commonly known as molds, refer to those that grow as multicellular colonies.	Fungi, Filamentous,Molds,Filamentous Fungi,Filamentous Fungus,Fungus,Fungus, Filamentous,Mold
D000447	Aldehydes	Organic compounds containing a carbonyl group in the form -CHO.	Aldehyde
D013109	Sphingomyelins	A class of sphingolipids found largely in the brain and other nervous tissue. They contain phosphocholine or phosphoethanolamine as their polar head group so therefore are the only sphingolipids classified as PHOSPHOLIPIDS.	Sphingomyelin