-transparent.png){kind=logo}
In 1988, we reported a thrombasthenic patient whose platelets contained an abnormal molecular weight GPIIb (Blood, 71, 915, 1988). Here we describe another patient whose platelets contain a variant GPIIb with properties similar to the previously reported abnormal GPIIb. This patient has a small amount of the abnormal GPIIb and was suggested to be a heterozygote characterized by deficient and abnormal GPIIb genes. The abnormal GPIIb was suggested to be related to the precursor form of GPIIb because the molecular weights of both proteins are the same. The abnormal GPIIb may lack a peptide region around the cleavage site of the two chains, as suggested from its lack of reactivity towards antibodies against these epitopes.
M Moroi, and
J Yamamura, and
H Koga, and
S Miyazaki, and
S M Jung
April 1988,
Blood,
M Moroi, and
J Yamamura, and
H Koga, and
S Miyazaki, and
S M Jung
March 1986,
British journal of haematology,
M Moroi, and
J Yamamura, and
H Koga, and
S Miyazaki, and
S M Jung
March 1987,
The Journal of clinical investigation,
M Moroi, and
J Yamamura, and
H Koga, and
S Miyazaki, and
S M Jung
December 2000,
British journal of haematology,
M Moroi, and
J Yamamura, and
H Koga, and
S Miyazaki, and
S M Jung
February 1999,
Blood,
M Moroi, and
J Yamamura, and
H Koga, and
S Miyazaki, and
S M Jung
June 1987,
The Journal of clinical investigation,
M Moroi, and
J Yamamura, and
H Koga, and
S Miyazaki, and
S M Jung
January 1983,
Comptes rendus des seances de l'Academie des sciences. Serie III, Sciences de la vie,
M Moroi, and
J Yamamura, and
H Koga, and
S Miyazaki, and
S M Jung
September 2001,
Blood,
M Moroi, and
J Yamamura, and
H Koga, and
S Miyazaki, and
S M Jung
July 1990,
Rinsho byori. The Japanese journal of clinical pathology,
M Moroi, and
J Yamamura, and
H Koga, and
S Miyazaki, and
S M Jung
February 1992,
The Journal of biological chemistry,
