Medium-to-long term DEXA analysis of an uncemented (AML) femoral component. 2008

K K Stöhr, and C Phillips, and J C Healy, and G Al-Yassiri, and C E R Gibbons
Department of Trauma and Orthopaedics, Chelsea and Westminster Hospital, London, UK.

We present medium-to-long-term bone mineral density studies assessing bone resorption and remodelling around the cementless femoral component of a total hip arthroplasty (Depuy AML prosthesis). Bone mineral densities were compared with the unoperated side at a time interval of eight years between scans using dual energy X-ray absorptiometry. Initial proximal stress shielding is known but we show that this response continues into the medium to long term in relative terms. We have also found an overall trend for bone mineral density to increase around the prosthesis with the greatest changes occurring distally. The greatest real increase in bone mineral density occurred in Gruen zones 2, 3 and 5 with smaller increases in zones 1, 4, 6 and 7. However, when compared with the contralateral unoperated femur (thus considering systemic changes in bone mineral density), we found these changes only reached statistical significance in Gruen zones 5, 6 and 7.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011474 Prosthesis Design The plan and delineation of prostheses in general or a specific prosthesis. Design, Prosthesis,Designs, Prosthesis,Prosthesis Designs
D002484 Cementation The joining of objects by means of a cement (e.g., in fracture fixation, such as in hip arthroplasty for joining of the acetabular component to the femoral component). In dentistry, it is used for the process of attaching parts of a tooth or restorative material to a natural tooth or for the attaching of orthodontic bands to teeth by means of an adhesive. Cementations
D005260 Female Females
D005269 Femur The longest and largest bone of the skeleton, it is situated between the hip and the knee. Trochanter,Greater Trochanter,Lesser Trochanter,Femurs,Greater Trochanters,Lesser Trochanters,Trochanter, Greater,Trochanter, Lesser,Trochanters,Trochanters, Greater,Trochanters, Lesser
D006622 Hip Prosthesis Replacement for a hip joint. Femoral Head Prosthesis,Femoral Head Prostheses,Hip Prostheses,Prostheses, Femoral Head,Prostheses, Hip,Prosthesis, Femoral Head,Prosthesis, Hip
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective

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