Biomaterial Database

[Ontogenic development of the incudostapedial joint]. 2008

Jaime Rafael Whyte Orozco, and Ana Isabel Cisneros Gimeno, and Carmen Yus Gotor, and Jesús Angel Obón Nogues, and Raúl Pérez Sanz, and José Francisco Gañet Solé, and Jesús José Fraile Rodrigo

Departamento de Anatomía e Histología Humanas, Universidad de Zaragoza, Zaragoza, España. jwhyte@unizar.es

OBJECTIVE To study the development of the incudostapedial joint in human embryos and foetuses. METHODS 46 temporal bones with specimens between 9 mm and newborns were studied. The preparations were sliced serially and dyed using the Martins trichrome technique. RESULTS The incudostapedial joint takes on the characteristics of a spheroidal joint at 16 weeks of development. The cartilage covering the articular surfaces is formed by different strata that develop in succession: the superficial stratum at 19 weeks, the transitional between 20 and 23 weeks, and the radial from 24 weeks on. The subchondral bone develops after 29 weeks by the mechanisms of apposition and extension of the periosteal and endosteal bones, but it is not until week 34 that it completely covers the articular surfaces, following constitution of the bone fascicles transmitting the lines of force. The articular capsule is formed from the inter-zone, the surface zone develops the capsular ligament, and the internal surface develops the synovial membrane. CONCLUSIONS At the time of birth, the incudostapedial joint is completely developed.

UI	MeSH Term	Description	Entries
D007188	Incus	One of three ossicles of the middle ear. It conducts sound vibrations from the MALLEUS to the STAPES.
D007596	Joints	Also known as articulations, these are points of connection between the ends of certain separate bones, or where the borders of other bones are juxtaposed.	Joint
D008022	Ligaments	Shiny, flexible bands of fibrous tissue connecting together articular extremities of bones. They are pliant, tough, and inextensile.	Interosseal Ligament,Interosseous Ligament,Interosseal Ligaments,Interosseous Ligaments,Ligament,Ligament, Interosseal,Ligament, Interosseous
D002356	Cartilage	A non-vascular form of connective tissue composed of CHONDROCYTES embedded in a matrix that includes CHONDROITIN SULFATE and various types of FIBRILLAR COLLAGEN. There are three major types: HYALINE CARTILAGE; FIBROCARTILAGE; and ELASTIC CARTILAGE.	Cartilages
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013199	Stapes	One of the three ossicles of the middle ear. It transmits sound vibrations from the INCUS to the internal ear (Ear, Internal see LABYRINTH).
D013701	Temporal Bone	Either of a pair of compound bones forming the lateral (left and right) surfaces and base of the skull which contains the organs of hearing. It is a large bone formed by the fusion of parts: the squamous (the flattened anterior-superior part), the tympanic (the curved anterior-inferior part), the mastoid (the irregular posterior portion), and the petrous (the part at the base of the skull).	Stylomastoid Foramen,Bone, Temporal,Temporal Bones
D047109	Fetal Development	Morphological and physiological development of FETUSES.	Fetal Programming,Fetal Growth,Development, Fetal,Fetal Programmings,Growth, Fetal