[Renin and aldosterone in the first 24 hours after acute myocardial infarct]. 1991

I Markuljak, and J Kvĕtenský, and S Funiak, and V Záhradný, and L Vladár
I. interná klinika, FNsP Martin.

The authors investigated the levels of plasma renin activity and aldosterone in patients with a fresh myocardial infarction during the first 24 hours of hospitalization. The values of plasma renin activity and aldosterone were correlated with values of the control group. At the time of admission to the clinic both hormones were significantly elevated, as compared with the control group, in plasma renin activity p less than 0.001 and in aldosterone p less than 0.01. During the subsequent time intervals, i.e. after 3, 6 and 24 hours, the values of plasma renin activity did not change substantially, while the aldosterone values declined during the 6th and 24th hour (significance p less than 0.05). No significant relationship was found between plasma renin activity an aldosterone. With regard to persisting elevated values of plasma renin activity the authors discuss the possible use of blockers of the angiotensin converting enzyme in order to inhibit in the initial stage of a new infarction the formation of endogenous pressor substances.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D009203 Myocardial Infarction NECROSIS of the MYOCARDIUM caused by an obstruction of the blood supply to the heart (CORONARY CIRCULATION). Cardiovascular Stroke,Heart Attack,Myocardial Infarct,Cardiovascular Strokes,Heart Attacks,Infarct, Myocardial,Infarction, Myocardial,Infarctions, Myocardial,Infarcts, Myocardial,Myocardial Infarctions,Myocardial Infarcts,Stroke, Cardiovascular,Strokes, Cardiovascular
D012083 Renin A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19. Angiotensin-Forming Enzyme,Angiotensinogenase,Big Renin,Cryorenin,Inactive Renin,Pre-Prorenin,Preprorenin,Prorenin,Angiotensin Forming Enzyme,Pre Prorenin,Renin, Big,Renin, Inactive
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000450 Aldosterone A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium. Aldosterone, (+-)-Isomer,Aldosterone, (11 beta,17 alpha)-Isomer
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor

Related Publications

I Markuljak, and J Kvĕtenský, and S Funiak, and V Záhradný, and L Vladár
March 1999, Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology,
I Markuljak, and J Kvĕtenský, and S Funiak, and V Záhradný, and L Vladár
January 1979, Bollettino della Societa italiana di cardiologia,
I Markuljak, and J Kvĕtenský, and S Funiak, and V Záhradný, and L Vladár
March 1983, Arquivos brasileiros de cardiologia,
I Markuljak, and J Kvĕtenský, and S Funiak, and V Záhradný, and L Vladár
September 1996, American family physician,
I Markuljak, and J Kvĕtenský, and S Funiak, and V Záhradný, and L Vladár
April 1988, British medical journal (Clinical research ed.),
I Markuljak, and J Kvĕtenský, and S Funiak, and V Záhradný, and L Vladár
April 1988, British medical journal (Clinical research ed.),
I Markuljak, and J Kvĕtenský, and S Funiak, and V Záhradný, and L Vladár
February 2002, Revista espanola de cardiologia,
I Markuljak, and J Kvĕtenský, and S Funiak, and V Záhradný, and L Vladár
April 1980, Soins; la revue de reference infirmiere,
I Markuljak, and J Kvĕtenský, and S Funiak, and V Záhradný, and L Vladár
April 1971, Klinicheskaia meditsina,
I Markuljak, and J Kvĕtenský, and S Funiak, and V Záhradný, and L Vladár
December 2009, Canadian journal of physiology and pharmacology,
Copied contents to your clipboard!