Electrophysiological outcomes after spinal cord injury. 2008

James Xie, and Maxwell Boakye
Neural Plasticity and Outcomes Research Laboratories, Veterans' Affairs Palo Alto Health Care System, Stanford, California, USA.

Electrophysiological measures can provide information that complements clinical assessments such as the American Spinal Injury Association sensory and motor scores in the evaluation of outcomes after spinal cord injury (SCI). The authors review and summarize the literature regarding tests that are most relevant to the study of SCI recovery--in particular, motor evoked potentials and somatosensory evoked potentials (SSEPs). In addition, they discuss the role of other tests, including F-wave nerve conductance tests and electromyography, sympathetic skin response, and the Hoffman reflex (H-reflex) test as well as the promise of dermatomal SSEPs and the electrical perceptual threshold test, newer quantitative tests of sensory function. It has been shown that motor evoked potential amplitudes improve with SCI recovery but latencies do not. Somatosensory evoked potentials are predictive of ambulatory capacity and hand function. Hoffman reflexes are present during spinal shock despite the loss of tendon reflexes, but their amplitudes increase with time after injury. Further, H-reflex modulation is reflective of changes in spinal excitability. While these tests have produced data that is congruent with clinical evaluations, they have yet to surpass clinical evaluations in predicting outcomes. Continuing research using these methodologies should yield a better understanding of the mechanisms behind SCI recovery and thus provide potentially greater predictive and evaluative power.

UI MeSH Term Description Entries
D009431 Neural Conduction The propagation of the NERVE IMPULSE along the nerve away from the site of an excitation stimulus. Nerve Conduction,Conduction, Nerve,Conduction, Neural,Conductions, Nerve,Conductions, Neural,Nerve Conductions,Neural Conductions
D004558 Electric Stimulation Use of electric potential or currents to elicit biological responses. Stimulation, Electric,Electrical Stimulation,Electric Stimulations,Electrical Stimulations,Stimulation, Electrical,Stimulations, Electric,Stimulations, Electrical
D004576 Electromyography Recording of the changes in electric potential of muscle by means of surface or needle electrodes. Electromyogram,Surface Electromyography,Electromyograms,Electromyographies,Electromyographies, Surface,Electromyography, Surface,Surface Electromyographies
D004594 Electrophysiology The study of the generation and behavior of electrical charges in living organisms particularly the nervous system and the effects of electricity on living organisms.
D005073 Evoked Potentials, Somatosensory The electric response evoked in the CEREBRAL CORTEX by stimulation along AFFERENT PATHWAYS from PERIPHERAL NERVES to CEREBRUM. Somatosensory Evoked Potentials,Evoked Potential, Somatosensory,Somatosensory Evoked Potential
D005712 Galvanic Skin Response A change in electrical resistance of the skin, occurring in emotion and in certain other conditions. Electric Conductance, Skin,Electrodermal Response,Reflex, Psychogalvanic,Skin Electric Conductance,Conductance, Skin Electric,Conductances, Skin Electric,Electric Conductances, Skin,Electrodermal Responses,Galvanic Skin Responses,Psychogalvanic Reflex,Response, Electrodermal,Response, Galvanic Skin,Responses, Electrodermal,Responses, Galvanic Skin,Skin Response, Galvanic,Skin Responses, Galvanic
D006181 H-Reflex A monosynaptic reflex elicited by stimulating a nerve, particularly the tibial nerve, with an electric shock. H Reflex,H-Reflexes,H Reflexes,Reflex, H
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D012684 Sensory Thresholds The minimum amount of stimulus energy necessary to elicit a sensory response. Sensory Threshold,Threshold, Sensory,Thresholds, Sensory

Related Publications

James Xie, and Maxwell Boakye
August 2020, Physical medicine and rehabilitation clinics of North America,
James Xie, and Maxwell Boakye
January 1997, Advances in neurology,
James Xie, and Maxwell Boakye
March 2013, Journal of neurotrauma,
James Xie, and Maxwell Boakye
June 2010, Spinal cord,
James Xie, and Maxwell Boakye
June 2020, Archives of physical medicine and rehabilitation,
James Xie, and Maxwell Boakye
April 2007, Brain : a journal of neurology,
James Xie, and Maxwell Boakye
January 2007, Journal of rehabilitation research and development,
James Xie, and Maxwell Boakye
March 1991, Archives of physical medicine and rehabilitation,
James Xie, and Maxwell Boakye
February 2005, Experimental neurology,
Copied contents to your clipboard!