-transparent.png){kind=logo}
The treatment of exponentially growing HeLa cells and quiescent WI-38 cells with cytochalasin D, which disrupts the cytoskeletal microfilaments, results in a rapid and marked increase in the transcription of the c-fos protooncogene with a concomitant increase in c-fos mRNA steady-state levels. Transcription of rRNA, HLA-B7, and H4 histone genes was not significantly affected by the drug treatment. These results suggest that the nucleus can respond to signals related to the structural organization of the cytoskeleton and selectively adjust the regulation of gene expression.
Related Publications
G Zambetti, and
A Ramsey-Ewing, and
R Bortell, and
G Stein, and
J Stein
July 1994,
The EMBO journal,
G Zambetti, and
A Ramsey-Ewing, and
R Bortell, and
G Stein, and
J Stein
October 1987,
Experimental cell research,
G Zambetti, and
A Ramsey-Ewing, and
R Bortell, and
G Stein, and
J Stein
December 2002,
Brain research,
G Zambetti, and
A Ramsey-Ewing, and
R Bortell, and
G Stein, and
J Stein
November 2009,
Journal of biomechanics,
G Zambetti, and
A Ramsey-Ewing, and
R Bortell, and
G Stein, and
J Stein
August 1993,
Brain research,
G Zambetti, and
A Ramsey-Ewing, and
R Bortell, and
G Stein, and
J Stein
February 1999,
Neuroscience letters,
G Zambetti, and
A Ramsey-Ewing, and
R Bortell, and
G Stein, and
J Stein
July 1990,
Experimental cell research,
G Zambetti, and
A Ramsey-Ewing, and
R Bortell, and
G Stein, and
J Stein
January 2004,
International journal of gynecological cancer : official journal of the International Gynecological Cancer Society,
G Zambetti, and
A Ramsey-Ewing, and
R Bortell, and
G Stein, and
J Stein
April 2012,
Psychopharmacology,
G Zambetti, and
A Ramsey-Ewing, and
R Bortell, and
G Stein, and
J Stein
January 1987,
Advances in experimental medicine and biology,
