Biomaterial Database

Aortic thrombosis after umbilical artery catheterization in neonates: prevalence of complications on long-term follow-up. 1991

J J Seibert, and F J Northington, and J F Miers, and B J Taylor

Department of Radiology, University of Arkansas for Medical Sciences, Little Rock 72202-3591.

We previously reported the early natural history of aortic thrombosis occurring after umbilical artery catheterization in 21 neonates. Ten of those neonates were reevaluated at 36-42 months of age for evidence of hypertension, renal abnormalities, and leg-growth disturbances. They were compared with an age-matched control group of seven infants. Blood pressures were greater than the 95th percentile in three infants and between the 50th and the 95th percentile in six of the 10 infants. Height was less than the fifth percentile for age in four infants with aortic thrombosis. One child had a 1.0-cm discrepancy in leg-length measurements, and seven of nine patients exhibited a 0.5-2.0 cm discrepancy between legs in either thigh or calf circumference. Sonography showed no evidence of residual clot in the aorta or renal vessels. Doppler flow was normal in all cases. Despite resolution of neonatal aortic thrombosis, complications resulting in renovascular hypertension (three of 10 patients) and leg-growth abnormalities (eight of nine) can occur. Hypertension (one of seven) and leg-growth discrepancy (four of seven) were less frequent in the 3-year follow-up of the seven matched control infants. We suggest that infants with known aortic thrombosis receive long-term follow-up to detect these potential problems.

UI	MeSH Term	Description	Entries
D006978	Hypertension, Renovascular	Hypertension due to RENAL ARTERY OBSTRUCTION or compression.	Hypertension, Goldblatt,Goldblatt Syndrome,Goldblatt Hypertension,Renovascular Hypertension,Syndrome, Goldblatt
D007231	Infant, Newborn	An infant during the first 28 days after birth.	Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D007870	Leg Length Inequality	A condition in which one of a pair of legs fails to grow as long as the other, which could result from injury or surgery.	Inequalities, Leg Length,Inequality, Leg Length,Leg Length Inequalities,Length Inequalities, Leg,Length Inequality, Leg
D008297	Male		Males
D002406	Catheterization, Peripheral	Insertion of a catheter into a peripheral artery, vein, or airway for diagnostic or therapeutic purposes.	Arterial Catheterization, Peripheral,Catheterization, Bronchial,Catheterization, Peripheral Arterial,Catheterization, Peripheral Venous,Peripheral Catheterization,Venous Catheterization, Peripheral,Bronchial Catheterization,PICC Line Catheterization,PICC Line Placement,PICC Placement,Peripheral Arterial Catheterization,Peripheral Venous Catheterization,Peripherally Inserted Central Catheter Line Insertion,Arterial Catheterizations, Peripheral,Bronchial Catheterizations,Catheterization, PICC Line,Catheterizations, Bronchial,Catheterizations, PICC Line,Catheterizations, Peripheral,Catheterizations, Peripheral Arterial,Catheterizations, Peripheral Venous,PICC Line Catheterizations,PICC Line Placements,PICC Placements,Peripheral Arterial Catheterizations,Peripheral Catheterizations,Peripheral Venous Catheterizations,Placement, PICC,Placement, PICC Line,Placements, PICC,Placements, PICC Line,Venous Catheterizations, Peripheral
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D005260	Female		Females
D005500	Follow-Up Studies	Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.	Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001018	Aortic Diseases	Pathological processes involving any part of the AORTA.	Aortic Disease,Disease, Aortic,Diseases, Aortic